Clinical Observation Of Kangshuan No.1 On Treatment Of Coronary Heart Disease (CHD) Combined With Type 2 Diabetesand Its Effect On Hemorrheology And Coagulation Function

Objective:To observe the Kangshuan NO.1 the clinical curative effect of treatment of coronary heart disease combined with type 2 diabetes and its vascular endothelin ET before and after treatment, plasma nitric oxide NO changes of relevant indexes, blood coagulation function and hemorrheology, evaluate its endothelial function in patients with coronary heart disease (CHD) with type 2 diabetes improved, antiplatelet and anticoagulant and improve blood flow state.Methods:50 patients with coronary heart disease (CHD) with type 2 diabetes, were randomly divided into control group and treatment group (n= 25).The control to the conventional western medicine treatment, the treatment group on the basis of conventional western medicine combined with Kangshuan NO.1,2 groups of treatment for 14 days. Observe two groups before and after treatment in angina pectoris curative effect, the main symptom integral and syndromes curative effect and the plasma ET 1, NO, coagulation function, hemorrheology index changes, such as statistics, comparing the difference between the two groups.Results:(1) Treatment group and control group in comparison with statistical significance (P< 0.05); (2) Symptoms integral:control group and treatment group respectively before and after medication main symptom integral is P< 0.05; Medicine control group and treatment group after the main symptom integral P< 0.05; (3) The doctor of traditional Chinese medicine syndrome after compared with control group (P< 0.05. That show the efficiency of the two groups after treatment was statistically significant; (4) The plasma ET and NO level changes:the control group and treatment group after ET value, NO value increases, ET, NO, P< 0.05, compared with this medication before ET control group P< 0.05, compared with the treatment group after the drug was NO control group and treatment group comparison (P< 0.01; (5) The blood coagulation function index:the control group and treatment group each medication before and after the blood coagulation function indicators are P< 0.05; After indicators and the treatment group to compare the control group (P< 0.05; (6) Hemorrheology related indicators:related to your group before and after medication hemorrheology indexes are P< 0.05; Treatment group and control group after hemorrheology index to compare P< 0.05.Conclusion:Kangshuan No.1 can obviously improve CHD-main symptoms of T2DM patients, improve the treatment efficiency and TCM syndrome, and has good security. Can significantly reduce plasma ET at the same time, improve the level of NO, improve blood coagulation function and related indexes. Prompt antithrombotic 1 protecting endothelial function, antiplatelet, improve blood viscosity and anticoagulation.