The Clinical Analysis Of Catheter Directed Thrombolysis In The Lower Extremity Deep Venous Thrombosis

Objective:To investigate the application and clinical efficiency of catheter-directed thrombolysis (CDT) and systematic thrombolysis in treatment for acute lower extremity deep venous thrombosis(LEDVT).Methods:Collect patients with acute lower extremity deep venous thrombosis from the center of Vascular Surgery in No.4hospital of Kunming Medical University between Oct.2014 and Sep.2015. Among 81 patients,46 cases treated by systematic thrombolysis represent Group A(control group),while 35 cases treated by catheter-directed thrombolysis represent Group B(treatment group).To estimate the effect of thrombolysis, a series of objective indexes were compared between the 2 groups, including clinical symptoms, changes of limbs circumference, and the results of angiography before and after treatment.Results:The clinical symptoms were improved and the swelling degree of one side limb has eased in both groups after treatment. In Group A, the swelling rate of patient’s upper legs and lower legs were (66.13±21.42)%and (67.74±21.72)%. In Group B,the swelling rate of patient’s upper legs and lower legs were (76.60±22.79)%and (78.77±20.79)%. The differences were statistically significant (p<0.05).The improvement rate of Group B was better than that of Group A in 3 days, which was statistically significant (p<0.05).While in 7 days, the improvement rate was not statistically significant (p>0.05). The complication rate of Group A was 8.70%,while the complication rate of Group B was 8.57%,which was not statistically significant (p>0.05).Conclusion:For patients with LEDVT, the efficiency of treatment by thrombolysis therapy can get better as soon as possible. Using catheter-directed thrombolysis can obtain clinical effect faster and have no increase in clinical complications.