Prevalence Of Chronic Kidney Disease And Associated Factors In The Fourth Division In Xinjiang Production & Construction Crops

Objective: To investigate the prevalence of chronic kidney disease(CKD) and risk factors in the adult population in the fourth division in Xinjiang Production & Construction Crops(XPCC).Methods: From November 2014 to April 2015, 4642 residents aged 30 years or over were randomly selected with stratified, multistage sampling method in 19 regiments from the fourth division in XPCC. All residents were interviewed and tested for morning spot urine of albumin to creatinine ratio(ACR)(abnormal:≥30 mg/g), morning spot urine dipstick of hematuria(abnormal:1+ or greater) confirmed by urine microscopy(abnormal:>3 red blood cells/HP) and MDRD equation estimated GFR [abnormal:<60ml/min/(1.73m2)]. The associations among demographic characteristics, health characteristics(e.g.smoking, alcohol, diabetes and hypertension) and indicators of kidney damage were examined.Results: A total of 4720 residents were involved in this survey. There are 4642 residents who had complete data were accounted in the study, the effective response rate was 98.3%. Among 4642 residents,the prevalence rate of CKD, albuminuria, renal function decrease were 15.2%,14.5%,1.3%, respectively.After the adjustment of sex and age component, the prevalence rate of CKD, albuminuria, renal function decrease, 14.7%, 14.0%, 1.4%, respectively. The prevalence rate of CKD1-5 stage were 10.4%, 3.5%,1.2%, 0.1%, 0%. CKD patients is given priority to the early stage(1~2 period). The prevalence of CKD was 12.9% in male, and 16.6% in female. Compare by sex, the prevalence rate of CKD of male was higher than female(P <0.01). The age is divided into six different age groups.The differences among age groups was statistically significant(P <0.01). The prevalence rate of CKD was increased with aging. The prevalence rate of CKD in Han ethnic was 15.5% and 13.2% in non-Han ethnic(Kazak and Uighur ethnic). Compare by ethnic, prevalence of CKD in Han and non-Han ethnic was not statistically significant(P>0.05).The results of multivariate logistic-regression analysis showed that age, sex, BMI,hypertension, diabetes, hyperuricemia, and hyperlipidemia were associated with CKD. The prevalence of hypertension, diabetes, hyperuricemia and hyperlipidemia was 45.3%, 10.9%, 5.3%, and 44%. Compared with non-CKD population, the prevalence of hypertension, diabetes, hyperlipidemia and hyperuricemia was significantly higher in CKD population(P <0.01).Conclusion:1. The prevalence rate of CKD in the aged 30 years or over of the fourth division in XPCC is higher, CKD stage 1-2 were dominated. The prevalence rate of CKD was increased with aging. 2.Compare by ethnic, prevalence of CKD in Han and non-Han ethnic(Kazak and Uighur ethnic) was not statistically significant in the aged 30 years or over of the fourth division in XPCC. Compare by sex,prevalence of CKD of male was higher than female. 3. The results of multivariate logistic-regression analysis showed that age, sex, BMI, hypertension, diabetes, hyperuricemia, and hyperlipidemia were associated with CKD. 4. Compared with non-CKD population, the prevalence rate of hypertension,diabetes, hyperlipidemia and hyperuricemia was significantly higher in CKD population.