Osteosarcoma is one of the most common malignant tumors in the young. Recurrence and metastatic osteosarcoma are not sensitive to a variety of treatments. Clinical needs new treatment options.Anti-angiogenic therapy is a new therapeutic approach for the treatment of malignant tumors, which is still at the exploratory. In this paper, research progress in the anti-angiogenic treatment of osteosarcoma will be reviewed. |