Research On Early Clinical Studies Of Using A New Zero-p Profile And A Titanium Plate With Cage Interbody Fixation And Fusion System In The Treatment Of Cervical Spondylosis

Background:It is notable to treat cervical spondylosis using the anterior cervical discectomy and fusion, but there are such complications as cervical instability and fusion rate low. Titanium plate with cage can solve those defects, while such complications as anterior unfamiliar matter and dysphagia. A new anterior cervical interbody fusion with support, fixation function has been widely used in clinical.Object: To analyze the early outcome of anterior cervical discectomy and fusion(ACDF) using a new Zero profile interbody fusion and a titanium plate with cage interbody fusion in the treatment of cervical spondylosis.Methods: we analyzed the clinical date of 31 patients with cervical spondylosis who under the anterior cervical discectomy and fusion(ACDF) in the Department of Orthopedics, Affiliated Hospital of Jiangsu University between August 2010 and December 2014.Fifteen patients were treated with a Zero-P implant(Group A) and sixteen patients with a titanium plate with cage(Group B). We sign up the operative time, intraoperative blood loss, preoperative and postoperative and final follow up Japanese Orthopedic Association(JOA) scores and JOA recovery rate, dysphagia incidence and its length of time and adjacent segment degeneration rate.Result: All the 31 patients had recovered obviously and no sever postoperative complications were found. The mean operate time in Group A and Group B was 105.67 min and 122.81 min, respectively. The average intraoperative blood loss in Group A and Group B was 104.67 ml and 150.00 ml, respectively. There were statistical differences in operation time and intraoperative blood between the two groups(P>0.05).The VAS and JOA score was significantly improved in the two groups(P<0.05), respectively. The recovery rate was similar(81.35% for Group A versus 81.17% for Group B, p>0.05).Dysphagia was experienced by one(6.67%) in Group A and nine(43.5%) in Group B, which was significantly different(P=0.037).There was no statistical significance difference in the adjacent level degeneration rates between Group A and Group B(P=0.48).Conclusion: In the anterior cervical discectomy and fusion(ACDF),using a new Zero-P and titanium plate with cage interbody fixation and fusion system were all good choices for cervical spondylosis while using the new Zero-P interbody fixation and fusion system could decrease the operative time and the incidence of postoperative dysphagia effectively.