| Depression is a common mental disease. There are mainly three clinical therapies for depression: pharmacotherapy, psychotherapy and physiotherapy. Some researches have shown that combining pharmacotherapy with a kind of new antipsychotics will probably be more effective in therapy. However it is still under dispute. Combining different types of antidepressants with Quetiapine(a new antipsychotic drug), We compare and summary its differences in therapeutic effect, onset time and side effects.We hope this article can supply clinicians with some reference to depression treatment. Combining antidepressants with Quetiapine will probably shorten the onset time of drug and improve the effect of treatment.But the chance of adverse reactions does not show an obvious increase. |