Reliability And Validity Of The Chinese Version Of EQ-5D In The Knee Osteoarthritis

Objective:Application of EQ-5Q scale and the MOS item short from health survey（SF-36）in patientswith KOA, comparison and analysis the data between EQ-5D and SF-36scale, studyEQ-5D’s reliability and validity in the field of knee osteoarthritis.Methods:In the investigation,we can see that the knee osteoarthritis patients have beendiagnosed in elderly osteoarthritis patients and BeiJing elderly hospital as the researchobject.The establishment of scale investigation team, for the survey of group training.Theinvestigation process:The patients of KOAwith MMES scale, selection of subjects; thepatients of KOA with EQ-5D scale and SF-36scale to fill in each survey are used, one toone question and answer form, require investigators ask each time line, to ensure that thesubjects understand the scale content and then record the answer, ensure the accuracy ofthe experimental results.The EQ-5D scale has carried out two times to fill in, the two timeinterval of two weeks; every time the end of the investigation were collected and the dataentry.Through the internal rank correlation coefficient evaluation scale test-retest reliability,Cronbach ’s alpha coefficient to evaluate the EQ-5D scale internal consistency, Pearsoncorrelation coefficient analysis test interrater reliability; scores and total scores of entries ofcorrelation analysis test content validity, comparative analyses of correlation measurementschool EQ-5D scale and SF-36scale standard validity.Results：1,The feasibility of scale:The collected a total of150subjects, the EQ-5D scale actualrecovery and effective completion of141cases, the effective rate of recovery is94%, theaverage test time is3minutes, EQ-5D scale has feasibility.2,The reliability of the scale:(1) The internal consistency reliability:In this study, EQ-5D scale Cronbach ’factor salpha coefficient was0.822, indicating that EQ-5D scale has good internal consistencyreliability.(2) The test-retest reliability: action, take care of yourself, daily activities, pain,anxiety, VAS intra class correlation coefficients were0.770(P<0.01),0.753(P<0.01),0.845(P<0.01),0.778(P<0.01),0.486(P<0.01),0.769(P<0.01), anxiety related minimumwithin class in0.486, the other dimensions of the correlation coefficient between the rangeof0.75~0.9. (3)Acopy of reliability: a questionnaire of1and VAS1was0.586(P<0.01),1and2for the0.885questionnaire questionnaire (P<0.01), a questionnaire of1and VAS2was0.624(P<0.01), a questionnaire of2and VAS2was0.635(P<0.01).3, The validity of the:(1)The content validity analysis: discussion by the panel, the EQ-5D scale has goodcontent validity; action, take care of yourself, Spearman correlation coefficient of dailyactivity, pain, anxiety and depression and the scores were-0.62(P<0.01),-0.320(P<0.01),-0.246(P<0.05),-0.840(P<0.01),-0.462Spearman (P<0.01), correlation coefficient VASand the score was0.586(P<0.01).(2) Construct validity: the correlation coefficient of action and take care of yourself,daily activities, pain, anxiety, VAS is respectively0.329,0.463(P<0.01),0.311(P<0.01),0.103(P>0.05),-0.306(P<0.01). The correlation between action and anxiety hassignificant correlation coefficient; take care of their daily activities, pain, anxiety and VASis respectively0.171(P>0.05),0.295(P<0.01),0.053(P>0.05,-0.173(P>0.05). The abilityto perform daily activities associated with pain, anxiety, VAS coefficient is0.229(P>0.05),-0.124(P>0.05),-0.262(P<0.01).(3) The criterion validity: anxiety and overall health, mental health, the total score ofSF-36, vitality, social function, emotional function correlation coefficient is-0.365,-0.262,-0.316,-0.451,-0.438,-0.438;0.308is the mental health related coefficient VAS andSF-36scale, and the correlation coefficient of SF-36total score was0.354.Conclusions:(1)The EQ-5D scale has good internal consistency, test-retest reliability and copyreliability. EQ-5D scale testing result has high reliability, the reliability is high inosteoarthritis of the knee area.(2)The EQ-5D content validity is high, good construct validity, and criterion validityof general SF-36.(3)The EQ-5D scale of reliability with high quality of life in patients with KOAandacceptable validity evaluation.