| Due to the unique structure of vesicles, they have many important applications in drug carrier, synthesis of nanoparticles and so on. Vesicles are divided into normal vesicles and reverse vesicles,which are formed in aqueous phase and organic phase respectively. In this article, we constructed normal and reverse vesicles by two different methods successfully. This article is divided into two parts:Firstly, in this article we prepared reverse vesicles on different substrate materials by using microemulsion(SDS, cyclohexane, n-butanol and H2O) for the first time. We chose carbon fibers which were soaked and unsoaked by acetone as substrate materials in order to study the influence of adsorption on the formation of reverse vesicles. And we also put the copper plate at the bottom of the confol dish to prepare reverse vesicles. It proves that the curvature is an essential factor for the formation of reverse vesicles. We chose a series of solvents to mix with cyclohexane and concluded that the hydrogen bond interaction is also the domain force to form reverse vesicles of EggPC. At the same time, we mixed sodium deoxycholate with EggPC to prepare lipid film and investigate its influence on the preparation of reverse vesicles. Also, we explored the mechanism of the reverse vesicle formation processSecondly, as the electrode material can affect the formation of vesicles, we made the modified copper electrode by electro-reduction of oxalic acid and given the copper electrode more excellent chemical properties. We applied it into the experiment of preparing vesicles. When the working electrode was copper electrode, no normal vesicles obtained. However, when the working electrode was oxalic acid modified copper electrode, we prepared giant normal vesicles with large size and stable property. In this article, we also study the influences of the voltage and frequency on the formation of normal vesicles. We found out the best voltage and frequency by experiment when preparing normal vesicles. |
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