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Synthesis Of Structure And Function Of Bionic Materials And Its Property Research

Posted on:2017-10-12Degree:MasterType:Thesis
Country:ChinaCandidate:Z Q GongFull Text:PDF
GTID:2311330485976451Subject:Materials engineering
Abstract/Summary:PDF Full Text Request
Bionics is an emerging science following by chemistry,systems biologist,molecular biology and nanotechnology's development.Biomimetic materials science refers to the characteristics of the mechanism research and the structure-activity relationship of biological materials from the molecular level.In people's daily life,people inspired by the special structure and function of the nature meterials.And began to imitate and use the biological structure to design and prepare the materials to obtain a new material that its properties are close to or even better than natural biological materials.Biomimetic biomaterials no only need the suitable mechanical and electrical properties,three-dimensional network structure and excellent cell/material interface,but also ask for good biocompatibility.Now,the biomimetic biomaterials develop fast,bionic biological material become one of the forefront hot spot of the research on the chemical,material,mechanics,physics,etc.This paper is based on bionic structure principle,we use the titanate nanowires of three dimensional network that prepared by hydrothermal method as the body of the bionic bone material.And then a layer of SiC nanometer column was used as the modified materials that was grown on the surface of the titanate nanowires by the magnetron sputtering method.Finally a bionic structure type nano biological bone materials of SiC/TiO2 was prepared.TiO2 has the advantage of high toughness and good imitation of the structure.But its strength is not good enough.SiC has the advantage of high hardness,abrasion resistant and good biocompatibility.To combine SiC with TiO2,we can give full play to their strengths and also can make up for their defects.Their structure were studied by scanning election microscopy?SEM?and transmission electron microscopy?TEM?,the electrical property was demonstrate by Force Measurement Analysis?FMA?software.More over,Cell viability was evaluated by MTT,sigma assay and retention of the osteoplastic phenotype was evaluated by measuring the alkaline phosphatase?ALP?test.The results were summarized as follows:1?The bionic structure type of SiC/TiO2 nanometer artificial material that was prepared by hydrothermal method,has three dimensional network structure similar to natural bone tissue.Through mechanics performance test?FMA?,It has excellent elasticity modulus and flexural compressive strength more than human bones.Single nanometer fiber of SiC/TiO2 bionic artificial bone material's bending elastic modulus K=13.5-25.0 GP that similar to the human body skeleton's bending elastic modulus K=17-18.9 GP.When bring external force to bear on the bionic artificial bone material,the material shows good toughness and compressive strength and bending strength.Secondly,This type of SiC/TiO2 bionic artificial bone material has good biological compatibility and biological activity.It can be used as a new generation of bone graft or the biological scaffold materials of bone repair.2?Bioglass with bionic structure shows similar structure to natural bone materials and complied with the principle of bionics that was prepared by the secondary hydrothermal method.At the same time,a zeolite molecular sieve was loaded on the silicate nanometers.It can not only increased the surface area and specific surface area of the bioglass to provide larger adhesion space for biological cells,but also increase the biocompatibility and cellular activity of the overall bioglass.Therefore it can promote the adhesion,proliferation and differentiation of the cell on the surface of bioglass.It can be used as a new generation of bone graft or the biological scaffold materials of bone repair.
Keywords/Search Tags:Biomimetic materials science, biomimetic materials, artificial bone materials, Bioactive glass
PDF Full Text Request
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