The Synthesis And Application Study Of 2-Acetyl-2-thiazoline

Although flavors and fragrances is not known by people,it also has the relationship with the national economy food,cosmetic,tobacco,pharmaceutical,feed and other industries supporting.The production of China is not only an important historic use of spices,spice trade is one of the most earliest country.Since the reform and opening up,China's sustained rapid economic development,flavors and fragrances important supporting industry ushered in a historic opportunity for development,as China's light industry products.Build with Chinese characteristics and cultural flavor and fragrance products.This paper describes the history of the flavor and fragrance industry,specifically the need for flavors and fragrances in people's daily lives.Synthetic methods are reviewed in the flavor and fragrance industry with a 2-acetyl-2-oxazoline of potential applications.Currently the industry 2-acetyl-2-thiazoline prepared to analyze the problems on how to improve synthesis of 2-acetyl-2-thiazoline were studied.Propose an economical synthetic route.By cysteamine hydrochloride intermediate product in an ethanol solution of sodium ethoxide in propionitrile reacted with ethanolamine under the ammonium acetate role,it will be generated under the action of an oxidant selenium dioxide solvent methylene chloride successful preparation of 2-acetyl 2-thiazoline.Under feasibility repeated verification test by comparison test,verify the side reactions reduce the yield of the existence of adverse reactions that occurred proposed principle,to provide a reference for subsequent optimization experiments.The gas and mass spectrometry detected the target product and proved the correction.Then the 2-acetyl-2-thiazoline safe storage and use of information was proposed.Summed up the advantages and disadvantages of this synthesis method,forecasting market was also demand for the product.Oriented products of industrial production and lay a solid foundation.