Studies On The Catalytic Hydrogenation Of Polar C=O And C=N Bonds Using An Air-Stable Iron Complex

Catalytic hydrogenation reactions,especially precious metal catalyzed hydroge nation reactions,has been widely applied in chemistry,chemical industry,energy and other fields because of its high activity and high atom economy.However,w e cannot ignore the problem of high cost and heavy metal toxicity.As the repres entative of the transition metal catalyst in the catalytic reaction,iron can avoid th ese deficiencies,reflecting its unique advantages-low toxicity,abundant,cheap an d readily available and changing valence and so on.Thus,the iron-catalyzed hydr ogenation reaction attracted widespread attention in recent years.This paper is div ided into three parts:Part Ⅰ:Review of the research progress on iron-catalyzed hydrogenation reaction of alkenes,alkynes,aldehydes,ketones,esters and imines in recent ten years.Part Ⅱ:Based on our previous research,we have successfully developed an air-stable iron complexe--dicarbonyl(pyridine)(η4-cyclopentadiene ketone)iron complex,which is high efficiency and high chemical selectivity for the hydrogenation of aldehydes,ketones and imines.We also made a preliminary study on the reaction mechanism,and proposed a possible reaction mechanism.Part III:Using dicarbonyl(pyridine)(η4-cyclopentadiene ketone)iron complex as the catalyst,we successfully synthesized polyfluorinated alcohols by catalytic hydrogenation of a series of polyfluorinated substituted carboxylic acid esters.In addition,we also proposed a possible reaction mechanism.