| Objective: Observe the curative effect and safety that the SHI PI YIN JIA WEI treat cases of heart spleen kidney Yang deficiency type of chronic heart failure, and plans for clinical treatment of chronic heart failure treatment to provide practical and valuable.Methods: According to include and exclude the standard, selected 60 cases of heilongjiang Chinese medicine academy of sciences, nangang Cardiology The second ward outpatient and hospitalized cases, and divided them into trial group and control group in accordance with the random number table. There are no statistical differences of two groups of patients with general data. Control group used conventional western medicine treatment, the experimental group was plused SHI PI YIN JIA WEI on the basis of conventional western medicine therapy, and oral warmly in half an hour after breakfast and dinner, one dose a day, twice a day, We assessed the clinical curative effect after 4 weeks. Systematically observed and compared the two groups of patients before and after treatment of traditional Chinese medicine syndrome integral, Lee’s integral, cardiac function classification of heart failure, echocardiography results(every cardiac output(SV), cardiac output( CO), left ventricular ejection fraction(LVEF)), six minutes’ walking test results and the NT- proBNP test results, the change of function of the liver and kidney.Observe two groups of patients the change of the blood, urine and stool before and after treatment.Results: After four weeks, therapy clinical studies confirmed that the experimental group in the cardiac function, lee’s integral, integral effect of lee’s heart failure and heart failure syndromes total curative effect is better than that in control group(P < 0.05); Single syndrome of traditional Chinese medicine curative effect analysis shows that the experimental group in the heart palpitations, chest tightness or chest pain, fatigue weakness, shortness of breath, Afraid of the cold,Eat less, diarrhea, edema, the improvement of the situation is better than that in control group(P <0.05); Experimental group in the tongue, tongue coating, pulse condition of improvement is better than that of control group(P < 0.05); Experimental group echocardiography results that increase the amplitude of every cardiac output(SV), cardiac output( CO), left ventricular ejection fraction(LVEF) is obviously better than that of control group(P < 0.05); Patients plasma NT- proBNP(N terminal brain peptide precursor) value of the reduction is better than control group(P <0.05);Experimental group in 6 minutes walk test walking distance(m) rises obviously better than that of control group(P < 0.05); Experimental group and control group had no obvious change of liver and kidney function, blood routine, routine urine routine before and after the treatment(P >0.05).Conclusion:The SHI PI YIN JIA WEI on the basis of conventional western medicine therapy can improve the clinical symptoms of patients with CHF, and improve the quality of life without toxic or sideeffect, and it is worth further research and extension. |
PDF Full Text Request