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Prognostic Value Of Neutrophil-To-Lymphocyte Ratio On Short-Term Outcomes In Acute Heart Failure

Posted on:2016-10-03Degree:MasterType:Thesis
Country:ChinaCandidate:H L FuFull Text:PDF
GTID:2334330482953526Subject:Internal Medicine
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ObjectiveThe aim of this study was to evaluate the association between NLR and short-term outcomes in patients admitted with AHF.MethodsThe study cohort consisted of 153 emergency patients admitted with acute heart failure, participants were divided according to low (?2.8) intermediate (2.8 to 5.0)?high (>5.0) tertiles of NLR and followed longitudinally for half year, the composite endpoint was readmission and cardiovascular mortality.ResultsA total of 52 patients(34%) occurred composite endpoint,high tertile had an increased rate (59.2%, n=52) compared to those in intermediate (42.3%, n=52) and low (21.2%, n=49) (P<0.001).In a multivariate regression analysis,compared with low tertile,the intermediate tertile HR was 2.85(95%CI 1.24-6.55, P=0.014),and the high tertile HR was 3.76(95%CI 1.52-9.34, P=0.004) after adjusting baseline demographic,pathogeny,clinical,biochemical and medicine covariates.In Kaplan-Meier curve analysis,elevated NLR is associated with outcomes of AHF(P=0.002).ConclusionNLR is a independent predictor of short-term outcomes in patients with AHF, which can be used as the risk stratification index in AHF patients.
Keywords/Search Tags:Neutrophil-to-Lymphocyte Ratio, Acute Heart Failure, prognosis
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