Impact Of Personality Traits On Brain Response To Acupuncture Stimuli

1 ObjectiveIn order to explore the effect of Personality traits on brain response to acupuncture with method of f MRI In order to observe the effects of electroacupuncture stimulation condition for Extraversion and neuroticism two different character types of brain activation change characteristics, the influence of different personality types is one of individual differences factors on brain response to acupuncture with method of f MRI.2 MethodsForty healthy volunteers of Extraversion and Neuroticism the two dimensions personality traits were selected from the NEO-FFI to participated this study. Task-state f MRI data were acquired while electroacupunctur at the bilateral point ST36(Zusanli) were performed. The functional data were acquired by a GRE-EPI sequence TR/TE/FA 2100ms/3.93ms/13°,FOV 250mm×250mm,, SL 1.0mm, spacing 0.75 mm, resolution256×256. Data were processed with the AFNI software and the activated brain areas were compared between the two groups. Intragroup analysis was done with one sample t-test(P=0.005, ?=0.01)and inter-group analysis was done with two samples t-test(P=0.005, ?=0.01) and were corrected with Monter Carlo method.3 ResultsIt was demonstrated that the brain activations in the group analysis were stronger and more extensive in Extraversion than in Neuroticism. Extraversion group: increased signal wase found in bilateral posterior central gyrus(right-BA40 and left-BA42), left declive, right superior frontal gyrus(BA10),left precental gyrus(BA6), left middle temporal gyrus, right culmen, left superior frontal gyrus, the bilateral middle frontal gyrus, and the right mediel frontal gyrus(BA32) was discreased signal area. Neuroticism group: right postrior central gyrus, left culmen, right inferior frontal gyrus, right precental gyrus, right inferior parietal lobule and cerebellum, these areas were positive activation. Compare with the Neuroticism group, increased activation in the left lingual gyrus and decreased activation in the right medial frontal gyrus was found in the Extraversion group.4 ConclusionsSignificant differences found in the brain response to acupuncture stimuli in different personality traits, therefore, difference in the personality traits may be an important contributor individual variability. superior medial gyrus, right inferior fontal gyrus, right anterior cingulate, left precuneus, left posterior cingulate, left superior temporal gyrus and the brain areas of decreased Reho were found in right inferior temporal Gyrus;...