| Objective:As is known to all thyroid disease is a common clinical endocrine system disease,and thyroid nodule is the common symptoms of thyroid disease.Thyroid nodule exist single but multiple;Thyroid can be found in the left lobe,the right page and spondylolysis.Even if occurred thyroid nodule,no obvious clinical symptoms existed generally,but the thyroid function abnormal can lead to obvious symptoms.Nodules in the laryngeal recurrent nerve compression,which could lead to voice hoarse;Nodules oppression throat may lead to symptoms,such as respiratory distress or swallowing difficulties.Further development of thyroid nodules,5% could progress to thyroid cancer,therefore it is very important for the early diagnosis and treatment of the disease.Surgical removal of the thyroid nodule treatments currently influenced largely on clinical prognosis.Method of colour doppler ultrasound mainly used in this research to exceed the civil servants,medical workers,power plant workers and university teachers,so as to count out the prevalence and the epidemiological characteristics in the different professionals,at the same time,combined with the research in recent years of thyroid nodule to explore the distribution of thyroid nodules disease,and to provide certain reference data for the establishment of prevention measures in the future.To date,nothing had been published about Shijiazhuang thyroid nodules about its risk factors and incidence.According to other parts of the previous research,we confirmed that such as age,gender,and family history had impact on the prevalence of thyroid nodules.We suspected that the incidence and prevalence in different career may also have differences,and finally found out the risk factors for neopathy nodules.Methods:1 Objects were chosed from January 1,2013 to December 31,2015 in the hospital check-up central.Four units were as listed: civil servants,power plant workers,university teachers,and the medical workers,and the regular physical examination results and thyroid colour doppler ultrasound to exceed established the basic data sources for this paper.The investigation,a total of 15,389 people,included 1,832 civil servants,3,047 power plant workers,4,678 university teachers and 5,724 medical workers in hospital;All the results of the research data were completed a total of 15,281 people,included 7,496 males and 7,785 females.At last,the prevalence of thyroid nodules were analyzed according to the medical report.2 To study the incidence of thyroid nodule,all the people established health records,matched the health archives information from January 1,2013 to December 31,2015,had been existing in the cohort of personnel information as follows: 581 civil servants,991 power plant employees,1,525 university teachers and 1,883 medical workers;finally the incidence of thyroid nodule from the investigation were checked.3 To affirm the prevalence and relevance of thyroid nodule with professional.4 At last,questionnaire survey was conducted on patients with neopathy thyroid disease.The age,sex,smoking history,drinking history and family history of family thyroid disease history in detail,screened the risk factors of neopathy thyroid diseases.Results:1 The basic information of civil servants,power plant worker,university teachers,and medical workers and the result of the prevalence of thyroid nodules.The basic situation of this research was as follows: 1,832 civil servants,4,678 university teacher,3,047 power plant workers,and 5,724 medical workers.Age distribution were 47.53 ± 11.69,49.58 ± 14.21,48.15 ±13.80,51.81±13.27.There was no age distribution difference,P>0.05.Civil servants gender distribution was 1,501 male(81.93%),university teachers’ gender distribution was 2,066 male(44.16%),Power plant on the worker’s gender distribution was 2,273 male(74.60%),and the gender distribution of medical workers was 1,656 male(28.93%).The survey results showed that civil servants,university teachers,power plant workers and medical workers thyroid nodule detection rate were 51.04%,52.44%,55.43%,68.11%;There was a difference between the four groups of detection of thyroid nodule,P<0.05,with statistical significance.Hospital medical workers and power plant workers thyroid nodule detection rate were higher than university teachers and civil servants.2 Compared the prevalence of thyroid nodules in civil servants,power plant workers,university teachers,and medical workersThe survey results showed that the gender distribution in civil servants thyroid nodule prevalence were 49.50% and 58.01%,university teachers’ thyroid nodule prevalence were 48.60% and 55.47%,power plant workers’ thyroid nodule prevalence were 50.99% and 68.68%,medical workers’ thyroid nodule prevalence were 64.13% and 69.74%;The thyroid nodule prevalence in civil servants,university teachers,as well as hospital medical workers was difference,P<0.05,with statistical significance.Medical workers and power plant workers thyroid nodule detection rate were higher than university teachers and civil servants.For analysis of four types of people of varying occupations,a thyroid nodule detection from 2013 to 2015 were made,any medical workers’ prevalence of thyroid nodule were higher than that in the rest of the professional personnel,P < 0.05,the difference was statistically significant.Further analysis for civil servants,contrasted in detail,at the same age different gender we found that: Although the prevalence of female was higher than that in male numerically,but statistically difference of only a few ages.Female in 2013 and 2015,41 to 50 ages,thyroid nodule prevalence was higher than male,P < 0.05,the difference was statistically significant.Further analysis for university teachers,contrasted in detail,at the same age different gender we found that: the prevalence in female is higher than that in male numerically,but statistically difference of only a few ages.In 2013,41 to 50 and> 60 ages;In 2014 and 2015,31 to 40 and 51 to 60 ages,the prevalence of thyroid nodule in female was higher than that in male,P < 0.05,the difference was statistically significant.Further analysis for power plant workers,contrasted in detail,at the same age different gender we found that,in the year of 2013 and 2015,41 to 50 ages,thyroid nodule prevalence in female was higher than that in male,P < 0.05,the difference was statistically significant.Further analysis for medical workers,contrasted in detail,at the same age different gender we found that,41-50 and > 60 ages in 2013;41-50 in 2014;31-40 and 41-50 in 2015;the prevalence of thyroid nodule in female was higher than that in male in the groups mentioned above,the difference was statistically significant,P<0.05.3 Compared the incidence of thyroid nodules in civil servants,power plant workers,university teachers,and medical workersDetected that had always been in the cohort from 2013 to 2015 in the department of civil servants,university teachers,power plant workers and medical workers,incidence of the thyroid nodules were accounted as 8.95% 8.95%,9.49% and 11.47% in their respective queue.For different professional groups,the incidence of thyroid nodule was different,the difference was statistically significant,P< 0.05.Medical workers has the highest incidence,power plant workers as followed.For the new examination of thyroid nodule,mapped the probability of different professional groups according to age graph,through which we could clearly observed at different occupations of thyroid nodules focus from 31 to 40,41 to 50 ages,and it could be seen that so as to power plant workers and medical workers,the incidence of thyroid nodule were ahead of schedule.4 According questionnaire investigation dispensed to the patients with neopathy thyroid diseases,we used group logistics regression to find out the risk factors that contributed to neopathy thyroid diseasesAnalysis results showed that the neopathy thyroid disease may risk factors were age,gender,engaged in different professional and smoking history.Female,age,work in the thermal radiation situation or psychological pressure,and smoking were more likely to help thyroid nodule change.Conclusions:1 The prevalence of thyroid nodule in female was generally higher than that in male,existed increasing trend of incidence with age and risen significantly after the age of 41.2 The incidence of thyroid nodule was different in different occupations,age peaks concentrated distribution between 41 and 60 years of age;Thyroid nodule peaks in the power plant workers and the medical workers could advanced to 30.3 The related risk factors for neopathy thyroid diseases mainly include: age,gender,smoking history and profession.Quitted smoking,kept away from the radiation heat source and the appropriated decompression as soon as possible,used gland colour doppler ultrasound to exceed check on a regular basis,might contribute to the primary prevention of thyroid disease. 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