Yunpi Decoction Combined With Acupuncture At Sifeng (EX-UE 10) Treatment Of Infantile Anorexia Spleen Fails To Transport And Transform Syndrome Clinical Observation

Objective:To evaluate the quality of the domestic clinical research literature on the treatment of infantile anorexia by the Yunpi method in the last twenty years.2 to evaluate the clinical effect advantages and feasibility of the Yunpi decoction combined with acupuncture at Sifeng (EX-UE 10) in the treatment of infantile anorexia of spleen fails to transport and transform syndrome,provide effective guidance for the treatment of children with anorexia.Methods:1 Retrieve domestic clinical research literature on the treatment of infantile anorexia by Yunpi method in January 1995-december 2015 domestic published,screened by the inclusion and exclusion criteria of the literature selection,to evaluate the quality of literature.2 Collected 60 cases of infantile anorexia of spleen fails to transport and transform syndrome of children, according to the random number table method divided into treatment group and control group, each group with 30 patients, treatment group treated with Yunpi decoction combined with acupuncture at Sifeng (EX-UE 10), Bifidobacterium tetravaccine tablets (Siliankang)were used to treat the control group,7 days for a course of treatment, continuous observation of four courses,quantitative score on the symptoms, record the changes in symptom score before and after treatment, the results were statistically analyzed to evaluate the efficacy of treatment.Results:Included in the evaluation of the 23 literatures, the quality of the literature were low. Meta analysis showed that Yunpi method in the treatment of infantile anorexia compared with Western medicine,Heterogeneity test analysis P=0.95>0.1,the included literature without heterogeneity, so used fixed effect model, the result showed that OR=6.71,95% CI [5.27,8.55], the combined effect Z=15.40, P<0.00001,the difference was significant Yunpi method endotherapy in the treatment of infantile anorexia compared with western medicine, heterogeneity test analysis P=0.86>0.1, without heterogeneity, so used the fixed effect model analysis, the result showed that OR=6.22,95% CI [4.59,8.41], the combined effect Z=11.85, P< 0.0001, the difference was significant,suggested that the Yunpi method endotherapy was better than western medicine treatment. Yunpi method external treatment compared with western medicine treatment, heterogeneous test analysis P=0.87>0.1, without heterogeneity,so used the fixed effects model, the result showed that OR=7.68,95%CI[5.12,11.53], the combined effect Z=9.84,P<0.0001, the difference was significant, suggested that the Yunpi method external treatment was better than western medicine treatment.2 In the treatment group,the cured,excellent, controlled, non-efecctived cases were 18,9,2,1;the control group were 10,10,7,3,after inspection, the comprehensive curative effect of the treatment group better than the control group(P<0.05).In the improvement of the main symptoms (appetite,intake), no significant difference between the two groups(P>0.05);In the improvement of secondary symptoms of complexion, eructation, nausea and vomiting, abdominal distension, tongue and pulse or fingerprint,the treatment group was better than the control group (P<0.05).Conclusion:1 The quality evaluation of clinical randomized controlled trials in the treatment of infantile anorexia by the Yunpi method, the literature quality was low, there were many problems in the design of the experiment, and the reliability of the conclusions.The results of Meta analysis showed that the treatment of infantile anorexia with spleen method was effective.2 Clinical research showed that Yunpi decoction combined with acupuncture at Sifeng (EX-UE 10) is showed that Yunpi decoction combined with acupuncture at Sifeng (EX-UE 10) in treatment of infantile anorexia of spleen failed to transport and transform syndrome compared with the control group of Bifidobacterium Tetravaccine tablets, in the improvement of secondary symptoms of complexion, eructation, nausea and vomiting, abdominal distension, tongue and pulse or fingerprint and the comprehensive curative effect was better.