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Application Of Serum Inflammatory Markers In The Evaluation Of Senile Pneumonia In Clinical Significance

Posted on:2017-05-18Degree:MasterType:Thesis
Country:ChinaCandidate:X BaoFull Text:PDF
GTID:2334330491961689Subject:Internal medicine of traditional Chinese medicine
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Objective:The aim of this paper is to explore the significance of serum inflammatory marker CRP, PCT in the diagnosis and treatment and prognosis of pneumonia in the elderly clinical and the relationship between sputum properties and inflammatory markers,And try to explore the diagnosis and treatment of pneumonia in the elderly combined with traditional Chinese medicine theory.Methods:Through the analysis of the patient's general condition on admission Age,gender,whether with basic nature of disease,clinical manifestation,sputum,sputum culture and CURB- 65 score,serum C-reactive protein and serum calcitonin original, blood leukocyte count,classification,treatment outcome of traditional Chinese medicine(whether death), And summarize the clinical features of senile pneumonia which combines traditional Chinese medicine with western medicine, Chinese medicine USES, properties and the relationship between inflammatory markers and sputum Inflammatory markers and prognosis evaluation of clinical significance of diagnosis and treatment of pneumonia in the elderly, the diagnosis and treatment of senile pneumonia.Results:1.Serum levels of PCT correlated with prognosis of death in patients with the highest(r=0.396), And the correlation was statistically significant(P = 0.000 < 0.05),Second death outcomes for patients with serum CRP and correlation(r=0.235),and correlation was statistically significant(P<0.05),The WBC correlated with prognosis of patients died without statistical significance(P>0.05).Further study on relationship between PCT and patient mortality found that threshold T=4.868 ng/mL,that is to say,when the PCT?4.868 ng/mL may predict mortality. 2.Yellow sputum culture bacteria positive rate of sputum group was obvi- ously higher than the yellow phlegm group, yellow sputum group of CRP averages of 82.984 + 62.233 mg/L,The yellow phlegm set of CRP averages of 29.161 + 35.447 mg/L,was statistically significant(P=0.000<0.05); Yellow phlegm group,the yellow sputum and PCT and CRP has relevance,and compared with PCT,the CRP value increased significantly, The PCT value increase is not obvious.Conclusion:1.In elderly patients with pneumonia after CURB-65 ? 3 points can effectively predict mortality;Serum PCT biggest correlation with prognosis of patients died(P<0.05),serum PCT test can be used as an important index in the evaluation of prognosis of senile pneumonia.And when the PCT?4.868 ng/mL may predict mortality.2. Compared with the serum PCT,serum CRP in elderly patients with pneumonia and yellow phlegm correlation is bigger,And yellow phlegm set of sputum culture bacteria in- fection positive rate than in sputum group is high,The significance of serum CRP to diagnosis of bacterial pneumonia in the elderly is bigger.
Keywords/Search Tags:Senile pneumonia, Yellow phlegm, Serum levels of inflammatory markers, C-reactive protein, Calcitonin original
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