Clinical Research Of Yiqiyangyinrunchang Decoction In The Treatment Of Senile Functional Constipation Of Qi And Yin Deficiency Type

Objective:By comparison with Macrogol4000 powder(trade name:Forlax),to observe the improvement of the clinical symptoms after using Yiqiyangyinrunchang Decoction on patients with senile constipation,to study its treatment effect and explore its therapeutic mechanism,thus to further evaluate the safety and efficacy of Yiqiyangyinrunchang decoction and the forward curative effect.And provide a scientific basis for clinical application.Methods:Choose the senile functional constipation 60 patients that visit to He Nan University of traditional Chinese medicine the Second Affiliated Hospital anus bowel division,between January 2015 and January 2016,and in line with the type of deficiency of both Qi and Yin.Accord each patient when visiting a doctor to make the EXCEL table.By using the method of random digits table,30 cases of treatment group and 30 cases of control group were divided into two groups.The treatment group using Yiqiyangyinrunchang Decoction,the control group using Forlax.Two groups were treated for a month,during the treatment,recorded the changes of the patients’ clinical symptoms and whether or not have adverse reactions.After the end of treatment,the clinical curative effect,the clinical symptoms score changes before and after treatment and the relapse after two months of withdrawal were analyzed by SPSS19.0 statistical software,in order to evaluate the clinical efficacy and safety.Results:(1)In terms of improved clinical total efficacy aspect:The treatment group total effective rate was 93.33%,and the control group total effective rate was 73.33%.After statistical analysis,the total effective rates of the two groups were significantly different(P < 0.05),with a statistical significance.This show that in improving the total clinical efficacy,the treatment group is better than the control group.(2)In improving the total clinical symptoms integral aspect:After the treatment,two groups of patients’ clinical symptom score were all decreased.Compared with before treatment,both the two groups have significant differences(P < 0.05).This shows that the treatment group and the control group with the two treatment methods both can improve the total clinical symptoms of elderly patients with functional constipation,but when compared with their total differences,a obvious distinction could be seen between the two groups(P<0.05),which certified that the treatment group had much more obvious curative effects than the control group.(3)In improving the clinical main symptoms integral aspect:After treatment,the main clinical symptoms such as defecation interval time,defecation time,the nature of the waste,difficulty of defecation,compared with before treatment,both of the two groups have significant differences(P<0.05),but when compared with their total differences,the treatment group had a significant distinction with the control group(P<0.05),which told that the treatment group had much better curative effects than the control one.(4)In improving the secondary symptoms integral aspect:After treatment,the secondary clinical symptoms such as shenpi lazy words,fatigue and shortness of breath,dizziness and tinnitus,hot flushes and sweats,compared with before treatment,both of the two groups have significant differences(P<0.05),but when compared with their total differences,in addition to the fatigue and shortness of breath integral difference(P > 0.05),the rest of the integral differences(P < 0.05),with statistical significance.The result indicates that the two groups were equivalent in treatment of fatigue and shortness of breath;the treatment group was significantly better than the control group in treatment of Shenpi lazy words,dizziness and tinnitus,hot flushes and sweats.(5)In the aspect of the recurrence rates:Followed up for two months after the end of treatment,the treatment group recurrence rates was 3.57%,while the control group was 22.73%,and there was a obvious distinction between the two groups(P<0.05),which told that the treatment group had a better long-term therapeutic effects than the control group.Conclusion:The tutor experienced prescription that Yiqiyangyinrunchang Decoction have obvious effect in improving clinical total effective rate,clinical total symptoms,clinical main symptoms,clinical secondary symptoms and recurrence rate.The effect is obviously better than the control group of Macrogol4000 powder(Forlax).It is worthy of clinical application.