The Comparative Research Of Two Kinds Of Titanium Alloy Products' Surface Feature Representation And Hemocompatibility

Objective:Titanium alloy productions' surface characteristics(white and black) of two kinds of different processing technology can be identified, and hemocompatibility can be evaluated, so it can provide theoretical basis for choosing suitable technological process.The surface composition and hemocompatibility of titanium alloys(white and black)using two kinds of different polishing techniques are identified and evaluated.Methods:The structure and surface physical and chemical properties of the titanium alloys were characterized by scanning electron microscopy(SEM), energy dispersive spectroscopy(EDS), atomic force microscopy(AFM), X-ray diffraction(XRD), X-ray photoelectron spectrometer(XPS). Hemocompatibility of titanium alloys was systematic evaluated by in vitro fibrinogen adsorption, platelet adhesion, platelet activation, clotting time, and in vivo implantation into dog's right atrium for 10 days.Results:The surface of white titanium alloy is thick and deep furrows and the ingredients are Ti, Al, V. While the surface of black titanium alloy is layered and superposed distribution,and the compositions are in addition to Ti, Al, V, and some impurities such as Si, Na, Ca,Fe, etc. The results of XRD show that the phase structure of two titanium alloys is titanium. XPS results show that the surfaces of both the titanium alloy form a very thinTiO2 thin film and the thin film of black titanium alloy is slightly thicker than white titanium alloy. The results of two kinds of titanium alloys' hemocompatibility have no significant difference by fibrinogen adsorption, platelet adhesion, platelet activation,clotting time in vitro. In vivo implantation experiment, the results show that the surfaces of both kinds of titanium alloys form thrombus. But black titanium alloy possesses markedly foreign body reaction and forms hyperplastic granulation tissue. And the visible components of surface adhesion in white titanium alloy are less than black titanium alloy.Conclusion:Combined with in vivo and in vitro experiment, the biocompatibility of white titanium alloy is superior to the black titanium alloy.