The Relationship Between TCM Syndrome Type Distribution Of Acute Cerebral Infarction And DWI/MRA And GCS/NIHSS Score

ObjectiveTo observe the nidus location and size of acute cerebral infarction and test the extent of obstruction and artery stenosis in intracranial vascular branches with different thickness by MRI-DWI/MRA examination. Then evaluated the score of GCS/NIHSS and assessed the type and severity of TCM syndrome. Finally, we detected the relationship between the five. MethersCollected the date of the nidus location, size and extent of intracranial artery stenosis in 238 cases of acute cerebral infarction patients through MR-DWI/MRA image data. Evaluated the score of GCS/NIHSS, and assessed the type and severity of TCM syndrome with the unified standard of Chinese medicine syndrome differentiation. Explored the relationship between MR-DWI/MRA image date(location, size and extent of intracranial artery stenosis), GCS/NIHSS score and TCM Syndrome type using statistical analysis. Results1 In this study, meridian was the main type of TCM syndrome. The wind phlegm into meridian was the most common type, following the wind due to yin deficiency and Yang wind disturbance syndrome. Viscera type was less which mainly was the phlegm heat and fu organ, the type of phlegm stasis fire shut was not been collected.2 In the large area cerebral infarction cases, the nidus in lobe was most, followed by basal ganglia, corona radiata and brainstem and cerebellum was less. In the focal cerebral infarction cases, the nidus was main in basal ganglia, lobe, corona radiata and brainstem while corpus callosum was less. In the corpus callosum cases, the nidus was main in brain stem, lobes and basal ganglia while the cerebellum and corpus callosum was less.The results suggested that the difference of the lesion site in different area of infarction was statistically significant(P < 0.01).3 Acute ischemic cerebral lesion main located in lobe and basal ganglia. Meridian of wind phlegm into collaterals, wind Yang nuisance and Yin pneumatic type were more common in lobe lesions. Secondly, the wind phlegm into collaterals and wind formation from Yin deficiency were common in basal ganglia, brainstem and corona radiata lesion. Finally, the wind phlegm into collaterals wasmian in thalamus lesion. Phlegm-heat accumulation was main in viscera in lobe in this study. The result suggested that the difference of TCM Syndrome Types in different parts of the infarction group was statistically significant(P < 0.01).4 The study demonstrated that the different type of TCM syndrome in different sizes of infarction focus group had statistical significance(P < 0.01). Yang wind disturbance type was main in meridian in large cerebral infarction. The wind phlegm into collaterals and wind formation from Yin deficiency were more common in focal brain infarction and lacunar cerebral infarction. Phlegm-heat accumulation was most common in large area of cerebral infarction in viscera.5 We analyzed the MRA date of large area infarction and focal infarction by chi square test. The result suggested that the type of abnormal vascular had a significant difference between large area infarction group and focal cerebral infarction group(P<0.01).6 The GCS score among three types of Apoplexy involving the channels and collaterals did not have statistical significance(P > 0.05). The GCS score among three types of apoplexy involving the viscera had statistical significance(P < 0.01). The GCS score of 4-8 points were considered the indicator of viscera of phlegm heat and fu organ sthenia syndrome, blood stasis and phlegm fire closed( no case) and closed phlegm turbidity and blood stasis. 3 points was considered the indicator of depletion of Yin Yang’s death. The GCS score was statistically significant in meridian group compared to viscera group(P<0.01).7 The NIHSS score among three types of meridian had statistical significance(P < 0.01). The NIHSS score among three quarters of viscera had statistical significance(P< 0.01). The NIHSS score in meridian group had statistically significance compared to viscera group(P < 0.01). The result suggested that difference of NIHSS score between meridian and viscera syndrome type group was statistically significant.Conclusion1 The type of TCM Syndromes of acute cerebral infarction could connect with the location of nidus. The ischemic infarction nidus of Wind phlegm in the collateralswere mostly located in the basal ganglia, lobe, thalamus, brainstem and corona radiata, Which could be taken as reference to the syndrome differentiation of objective indicators. The ischemic infarction lesion of wind formation from Yin deficiency were mostly be found in lobes, basal ganglia, brainstem and corona radiata, Which could be taken as reference to the syndrome differentiation of objective indicators. The ischemic infarction lesion of Yang wind and disturbance of phlegm heat and fu organ were mostly located in lobes,Which could be taken as reference to the syndrome differentiation of objective indicators.2 The type of TCM Syndromes of acute cerebral infarction could connect with the size of lesion. Large cerebral infarction were mostly be link to Yang wind disturbance type and phlegm heat and fu organ,Which could be taken as reference to the syndrome differentiation of objective indicators. Focal and lacunar cerebral infarction were mostly be link to wind phlegm into collaterals and wind formation from Yin deficiency,Which could be taken as reference to the syndrome differentiation of objective indicators.3 DWI combined with MRA was an effective means for observation and diagnosis of acute ischemic cerebral infarction, and could comprehensively evaluated the condition and determined the prognosis.4 Arterial occlusion was the main presentation in large area infarction group,while arterial stenosis and arteriosclerosis was the main presentation in focal area infarction group.5 The Glasgow Coma Scale(GCS) score could be used as the reference index for viscera, and the NIHSS score for various types of meridian.