Lung Adenocarcinoma With GGO Nodules:HRCT Radiological And Pathological Correlation

BackgroundLung cancer is the most common cancer related death in the world for both the sex male as well as female. Adenocarcinoma is the most common pathological types which is in increasing trend. With recent advancement of screening of lung cancer with HRCT, GGO lesion has been noted frequently. GGO is nonspecific findings that may be caused by various disorders including inflammatory disorders, focal fibrosis, atypical adenomatous hyperplasia (AAH), adenocarcinoma in situ (AIS) and adenocarcinoma. This study tends to analyze the correlation between High resolutions computed tomography (HRCT) findings and the pathological findings of lung adenocarcinoma.Material and methodsRetrospective review of 16 cases of lung adenocarcinoma lesions after surgical resection. Tumors were defined as air containing type based on ratio of maximum dimension of the tumor on mediastinal window to the maximum diameter of the tumor on lung window was≤50% and as solid density if the ration was >50%. The correlation between CT findings (homogenous/heterogeneous, airbronchogram, pleural tag, speculation, vascular involvement, pleural thickening, margin, shape) and pathological findings were investigated.ResultOf 3 air containing types GGO nodules 2 were pre-invasive type and 1 was invasive. Among 13 solid density types GGO nodules all 13 were invasive type. Presence of speculation, heterogeneous appearance was found significantly associated with pathological invasion.ConclusionAir containing types of small cells lung adenocarcinoma were pre-invasive whereas solid densities were invasive. Speculation and heterogeneous were significant factor in invasive adenocarcinoma.