The Clinical Research About Ultrasound Guided Laser Ablation Of Papillary Thyroid Micro-carcinoma

Objective: 1. To evaluate the therapeutic effect of ultrasound guided percutaneous laser ablation using in Papillary Thyroid Microcarcinoma; 2. To indentify the prognosis of the patients who underwent ultrasound guided percutaneous laser ablation because of Papillary Thyroid Microcarcinoma; 3. To compare the ultrasound guided percutaneous laser ablation with the surgical treatment of Papillary Thyroid Microcarcinoma in order to assess the advantages and disadvantages of two methods.Methods: 1. A total of 35 cases, from December 2013 to December 2014, were confirmed PTMC by US – FNAB. All patients requested percutaneous laser ablation voluntarily. After the risk and possible complications of percutaneous laser ablation sufficiently explained, they were asked to sign the informed contents. The treatment time, energy, and symptoms in operation were recorded, then using contrast enhanced ultrasound to access the results. 2. During the follow-up period, patients who were treated by percutaneous laser ablation would be visited, the follow-up contents included the change of the ablation area volume, thyroid function, postoperative symptoms and complications, recurrence and metastasis and postoperative biopsy. 3. 34 cases that had thyroid operations in the general surgery department from May 2014 to November 2014 were selected as the control group, and operating time, length of hospital stay, complications, pain score, and appearance evaluation of two treatment methods had be recorded respectively.Results: 1. Single treatment effectiveness of percutaneous laser ablation was 100%. In the process of the treatment, there were no other symptoms except painfulness. 2. After percutaneous laser ablation, no serious complications had been observed,the volume of ablation area shrinked gradually. No recurrence and metastasis were observed in the following 12 months. Before treatment and follow-up duration, there was no difference regarding thyroid function(P<0.01); 1 month, 6 months and 12 months after the treatment, the result of US-FNAB showed no tumor cell of the lesion. 3.Considering the operation time, pain score, and the length of time, differences between PLA group and surgical treatment were significant(P<0.001). PLA group had higher satisfaction on postoperative appearance evaluation.Conclusions:1. Ultrasound guided percutaneous laser ablation can be a useful method applying to treatment of selected patients with Papillary Thyroid Microcarcinoma. 2. There is a great prognosis for the patients treated by Papillary Thyro id Microcarcinoma. 3. Comparing with the traditional surgery, the ultrasound guided percutaneous laser ablation had obvious superiority in treating selected Papillary Thyroid Microcarcinoma.