Comparative Study Of Cardiac Function After Aortic Valve Replacement With Biological And Mechanical Valve

Objective: To collect patients from January 2010 to October 2015 who are under cardiopulmonary bypass of aortic valve replacement in department of C a r d i ac S u rg e r y, G e n er a l H o s p i t a l O f N i n g xi a M e d ic a l U n i v e r s i t y(30 cases replace mechanical valve and 30 cases replace biological valve).All patients were examined by color doppler ultrasound in the preoperative and early postoperative(in 10 days),analysis those indicators,and then to evaluate the effects of biological and mechanical valve on the recovery of cardiac function in patients with early postoperative,and to further understand the application of the biological and mechanical valve in aortic valve replacement.Methods:All patients were examined by color doppler ultrasound in the preoperative and early postoperative,including the ascending aorta diameter, left ventricular end-diastolic diameter, left ventricular ejection fraction, aortic valve transmittal pressure difference,after that,then compare those indicators, and to do the statistical analysis, and to list the general information of patients at last.Result: Mechanical valve group of patients with early postoperative in the ascending aorta(AAD) 34.53 ± 5.5mm, left ventricular end-diastolic diameter(LVDd) 55.03 ± 11.6mm and aortic valve transmittal pressure difference 23.42 ± 12.9mm Hg were both reduced than preoperative36.43 ± 5.5mm ?66.73 ± 12.2mm ? 39.70 ± 28.9mm Hg and the difference was statistically significant(P < 0.05) before the operation.But in the early postoperative left ventricular ejection fraction(LVEF) 56.93 ± 11.8% compared with preoperative 56.91 ± 11.5% was no statistical significance(p > 0.05).To biological valve group, the early postoperative in ascending aortic diameter(AAD) 335.93 ± 4.5mm, left ventricular end diastolic diameter(LVDD)49.87 ± 10.2mm and aortic valve transmittal pressure difference 22.85 ± 10.5mm Hg were both reduced compare with preoperative 38.97 ± 5.2mm, 62.53 ± 13.2mm, 41.39 ± 33.4mm Hg and the difference was statistically significant(P < 0.05) before the operation.But in the early postoperative left ventricular ejection fraction(LVEF) 54.84 ± 11.5% compared with preoperative 56.99 ± 10.4% was no statistically significance(p > 0.05).Mechanical valve group in ascending aortic diameter(AAD), left ventricular end diastolic diameter(LVDD), left ventricular shoot ejection fraction(LVEF) and aortic valve transmittal pressure difference of preoperative and postoperative difference(difference = preoperative index- postoperative index) 1.90 ± 3.1mm ? 11.70 ± 5.9mm ?-0.02 ± 8.4%? 15.65 ± 18.0mm Hg compared with biological valve group index of preoperative and postoperative difference 3.03 ± 4.3mm ? 12.67 ± 12.1mm ?2.15 ± 11.5%? 18.54 ± 26.6mm Hg,the difference was not statistically significant(P > 0.05).Conclusion: In aortic valve replacement, for early postoperative cardiac function changes in the ascending aorta diameter(AAD), left ventricular end-diastolic diameter(LVDd), left ventricular ejection fraction and aortic valve transmittal pressure difference was no significant difference whether it is a mechanical valve replacement or biological valve replacement.Regardless of mechanical valve replacement or biological valve replacement in patients, early postoperative cardiac function compared with preoperative in the ascending aorta diameter(AAD), left ventricular end-diastolic diameter(LVDd) and aortic valve transmittal pressure difference were reduced, and in the left ventricular ejection fraction was no significant difference.