Study On The Correlation Between The Distribution Of TCM Constitution Of The Primary Dyslipidemia And The Carotid Antherosclerosis In Middle-aged And Elderly Patients

Objective:To investigate the characteristics of physical constitution of Middle-aged and elderly patients with primary dyslipidemia.To explore the relationship between TCM constitution and carotid atherosclerosis.Our goal is to provide a basis for predicting the occurrence of carotid atherosclerotic from the perspective of Chinese medicine.Methods:We choose a total of 160 eligible patients with primary dyslipidemia were diagnosed from the hospital.All subjects were asked to complete face-to-face interviews by trained interviewers using astructured questionnaire.Select the most distributed three types of physical to do carotid artery ultrasonography.To compare the general situation,blood lipid,carotid intima-media thickness,carotid atherosclerotic plaque,plaque stability,vascular stenosis,hemodynamics of three kinds of physical We use SPSS20 software system for data analysis.Results:1.The distribution Types of TCM of 160 cases people with primary dyslipidemia:The Phlegm in 35 cases(22%),Qi deficient physical in 30 cases(19%),Yang deficient physical in 28 cases(17.5%),Ecchymosis physical in 22 cases(14%),Yin deficient physical in 20 patients(12.5%),Moderate physical in15 cases(9%),Hot and humid physical in 8 cases(5%),Qi stagnation in 2 cases(1%),special intrinsic physical in 0 cases(0%).2.The incidence of carotid intima-media thickness and carotid atherosclerotic plaques were highest in the phlegm-dampness,the differences between Phlegm and qi-deficiency,yang-deficiency group were statistically significant(P<0.05).The vascular stenosis rate of Phlegm was higher than other physical,the differences between Phlegm and yang-deficiency group were statistically significant(P<0.05).There was no statistically significant difference between the other groups(P>0.05).3.The difference in PSV of left carotid artery was statistically significant,and phlegm is the lowest,the differences between Phlegm and Qi deficiency,yang-deficiency group were statistically significant(P<0.05);PSV of right carotid was not statistically significant after analysis(P>0.05).There was a significant difference in the right RI between the phlegm,qi deficiency and yang deficiency(P<0.05).There was a significant difference in the left RI between the phlegm and yang deficiency(P<0.05).4.There were significant differences in the plaque nature of carotid artery between phlegm dampness,qi deficiency,yang deficiency(P<0.05).The incidence of unstable plaque in qi deficiency was higher than the other physical.5.The differences of TC,HDL-C and LDL-C between the three groups were statistically significant(P<0.05).There were significant differences between phlegm-dampness and qi deficiency and yang deficiency in TC,HDL-C(P<0.05).There was significant difference between phlegm-dampness and yang deficiency in LDL-C(P<0.05).TG was not statistically significant after analysis(P>0.05).Conclusions:1.In the elderly patients with primary dyslipidemia,the main physical were Phlegm-dampness,Qi deficiency and Yang deficiency.2.Phlegm-dampness physical in middle-aged and elderly patients with dyslipidemia are more likely to form carotid intima thickening,carotid atherosclerotic plaque,vascular stenosis and hemodynamic changes.3.Qi deficiency in middle-aged and elderly patients with dyslipidemia are more likely to form unstable plaque which leads to the risk of arterial infarction.4.Phlegm-dampness can indirectly promote the occurrence of atherosclerosis by influencing the level of lipid metabolism.