A Feasibility Study Of Cervical Cancer Screening Risk Assessment Scale

Objective In this study,the parameters such as age,maternal age,number of sexual partners,history of alcohol and tobacco,educational level,gynecological symptoms,signs,TCT-HPV and epidemiology were selected as questionnaire,and the independent variables were analyzed retrospectively,And the correlations of risk between cervical cancer and variables were analyzed.Then the variables were quantified and last to design a Cervical Cancer Screening Risk Assessment Scale and analyze its feasibility,providing guidance for clinical cervical cancer screening.Methods A total of 200 cases of gynecological outpatients from Anqing Hospital Affiliated to Anhui Medical University from December 2015 to June 2016 were collected,including 132 cases of benign cervical lesions(cervical inflammatory diseases)and 68 cases of cervical diseases(Cervical intraepithelial neoplasia and cervical cancer).The data were analyzed by the u-test and multivariate logistic regression analysis.Then the threshold value was thrived by results of the ROC(Receiver Operating Characteris)curve analysis.After these independent variables were screened and analyzed,the Cervix Screening Risk Assessment Scale(CSRAS,L-Y-01)was developed.Finally,70 new patients were enrolled to reassess and validate the scale.Results The results of this study established a new digital model of cervical screening,which leads to a 12-point risk threshold.According to the model,if the total score of patient screening was < 12 points,the final histopathological examination results tended to be benign lesions,which can avoid invasive examination and over-treatment.Conversely,if the total score of patient screening was ? 12 points,the patient's histopathological examination results tend to non-benign lesions,needing to refer to the colposcopy for further examination.The use of scales could reduce the misdiagnosis and missed diagnosis caused by false negative or false positives of individual inspection.Conclusion The results show that the risk threshold can be used to assess the risk of cervical disease screening,and the concept of this study is consistent with the current "risk quantification,hierarchical management" concept.