| Objective: To evaluate the therapeutic effect of Shugan Jieyu Capsule on anxiety and anxiety of patients with coronary heart disease complicated with early stage of liver depression and spleen deficiency.In this study,only 81 cases of coronary heart disease intervention with early liver depression and spleen deficiency type of anxiety patients to show that Shugan Jieyu capsule in patients with postoperative coronary heart disease associated with early liver depression and spleen deficiency type of anxiety And application prospects.Methods: Randomly selected from November 1,2014 to October 1,2016 of stent implantation in coronary artery disease in the Department of cardiology ward,outpatient department of Cardiology,Second Affiliated Hospital of Dalian Medical University of traditional Chinese medicine,Chinese medicine outpatient wards,neurology wards,neurology clinics and psychological counseling room after 150 patients as the research object,using questionnaires to guide them to fill out the Hamilton Anxiety Scale(HAMA),select the score more than 14 points and combined with generalized anxiety disorder and 81 patients were tested for 8 weeks,divided into Shuganjieyu capsule group,Deanxit group,combination group and three groups,respectively before and after treatment in 2,4 and 8 weeks in HAMA(Hamilton Anxiety Rating Scale table),TCM syndrome score.And before treatment and after 8 weeks respectively fill out the SAQ scale(Seattle angina scale),during the test closely observe the occurrence of adverse reactions,serious adverse reactions,timely termination of the test.Result:Before and after 0.05 weeks treatment,the HAMA score of group 2 was compared with P > 1,which was not statistically significant.After 4 weeks and 8 weeks,the score was significantly improved(P < 0.01).Group 2 and 3 respectively in 2 weeks and 4weeks after the HAMA score was significantly improved compared with before treatment(P < 0.01),after 8 weeks of treatment,2 groups showed no significant difference(P > 0.05),the 3 groups after 8 weeks of treatment,the integral significantly improved(P < 0.01).After weeks treatment,the scores of anxiety in group 3 were significantly better than that in group 1 and group 2(P < 0.01)after 2 weeks of treatment.Group 2 was better than group 1(P < 0.01).4 weeks after the group 3 of the anxiety score is still significantly better than the group 1.There was no significant difference between the 2 groups(P > 0.05).After 8 weeks treatment,the anxiety score of group 3 was significantly better than that of group 2(P < 0.01),and there was no significant difference between the 1 groups(P > 0.05),which showed that the two groups had a significant effect after 8 weeks.The efficacy score of group 1 was better than that of group 2(P < 0.05).The three groups of 2 weeks of treatment of traditional Chinese medicine symptoms were significantly improved(P < 0.01).After 4 weeks of treatment,1 of the group remained significantly improved,and the group 3 was improved.After 8 weeks,there was no significant statistical significance(P > 0.05).Compared with the traditional Chinese medicine symptom score group,2 weeks after treatment group 2compared with the group of 3 Chinese medicine symptoms,there was significant statistical difference(P < 0.01).Group 2 and group 3,group 1 and group 3 were statistically significant(P < 0.05).After 4 weeks of treatment group 3 and group 2,compared with traditional Chinese medicine symptoms,there was significant statistical difference(P < 0.01).Group 1,group 2 and group 3 after treatment PL(physical limitation(AS),angina stability),AF(angina pectoris),with significant difference(P < 0.01),group 2 and group 3 after treatment(TS treatment satisfaction)there is statistically significant difference in group between(P < 0.01),group 1 and group 3 DS after treatment(diseasecognitive level)than before treatment significantly improved(P < 0.01)The anxiety score comparison: group 1 after 2 weeks of treatment,the total efficiency of 11.1%;4 weeks,the total efficiency of 51.9%;8 weeks,the total efficiency of 100%;the 2 group after 2 weeks of treatment,the total efficiency of 88.9%;4 weeks,the total efficiency of 88.9%;8 weeks,the total efficiency of 81.5%;the 3 group after 2weeks of treatment,the total efficiency of 92.6%;4 weeks the total efficiency of 100%;the total effective rate was 100% in 8 weeks.Total effective rate group 2 > group 3 >group 1.Comparison of TCM symptoms: 1 groups after 2 weeks of treatment,the total efficiency of 81.5%;4 weeks,the total efficiency of 88.9%;8 Zhou Zong efficiency of88.9%;group 2 after 2 weeks of treatment,the total efficiency of 74.1%;4 weeks,the total efficiency of 100%;8 weeks,the total efficiency of 100%;the 3 group after 2weeks of treatment,the total efficiency of 100%;4 weeks the total efficiency of 100%;8 weeks,the total efficiency of 100%.Total effective rate group 2 > group 3 > group 1.Conclusion:1 Shuganjieyu capsule is effective to relieve the patients with coronary heart disease after intervention of anxiety symptoms,improve chest pain,palpitations shortness of breath,upset,insomnia,sigh and other clinical symptoms,reduce the level of physical activity limitation and angina pectoris,improve angina stability and treatment of cognitive satisfaction and disease degree.2 Shugan Jieyu capsule and deanxit two drugs can play a synergistic effect.3 Compared with Deanxit,Shuganjieyu capsule slow onset,mild effect,no curative effect of Deanxit and combination of two drugs was not suitable for acute disease. |
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