| Object:A total of 49 patients with Achalasia(AC)who were diagnosed by barium meal,endoscopy or HRM in Dalian Central Hospital of China from 2010.Jan—2017.Jan were retrospectively analyzed.The common information,diagnosis data and treatment data were analyzed.To Summarize the clinical characteristics of patients with AC,and to explore the clinical significance of different methods of examination.Method:The clinical data of 49 patients with AC who were hospitalized in Dalian Central Hospital from January 2010 to January 2010 were retrospectively analyzed.To count their general information,incentives and risk factors,clinical manifestations,combined disease,imaging examination,endoscopy and treatment methods.Results: 1.The age of 49 cases patients with AC is 22-91 years old,age data were normal distribution,the average age is(54.45 ± 16.65)years old,60-69 years old is the most.26 males(53.06%),23 females(46.94%),the ratio of male to female is 1.1: 1,There were no significant differences between the two groups(P> 0.05).The average age of males is(53.54 ± 18.23)years old years old and the average age of females is(55.48 ± 15.00)years old.There was no significant difference in male and female age(P> 0.05).2.There were 11 cases(22.45%)in the young group(0-39 years old),including 7 males and 4 females,and 17 cases(34.69%)in the middle age group(40-59 years old),including 9 males and 8 females,and 21 cases(42.86%)in the elderly group(? 60 years old),including 10 males and 11 females.There was no significant difference in sex composition at different ages(P> 0.05).3.There were 8 patients(16.33%)with incentives and there was a significant difference between incentives and no inducements(P <0.05).The more AC patients have no clear incentive.Incentives were emotional,mental stress,eating some kind of food,there were no significant differences in the composition of the three kinds of incentives(P> 0.05).13 cases(26.53%)had smoking history and 13 cases(26.53%)had drinking history.The proportion of smokers and non-smokers was statistically different(P <0.05),and the proportion of non-smokers was slightly higher.The proportion of drinkers and non-drinkers was statistically different(P <0.05),and the proportion of non-drinkers was slightly higher.4.The proportion of symptoms of AC patients is dysphagia 40 cases(81.63%),reflux 19 cases(38.78%),weight loss 16 cases(32.65%),nausea and vomiting 13 cases(26.53%),chest pain 10 cases(20.41%),upper abdominal distension(12.24%),upper abdominal pain(8.16%)from more to less.5.Dysuria,nausea and vomiting were correlated with gender(P <0.05).It Can not determine the reflux,weight loss,chest pain,upper abdominal discomfort or pain were related with gender(all P <0.05).6.AC patients with esophageal-related diseases were mainly 5 cases of esophageal reflux disease(10.20%),3 cases of esophageal hiatus(6.12%),2 cases of esophageal diverticulum(4.08%),1 case of esophageal fungal infection(2.04%),1 case of esophageal ulcer(2.04%),1 case of esophageal tracheal fistula(2.04%),1 case of esophageal cancer(2.04%).7.There were significant differences between Barium radiography and endoscopy of AC(P <0.05).8.The incidence of dysphagia of type ? was higher than that of type?,but there was no significant difference(P> 0.05).The incidence of reflux of type ?was higher than that of type ?,which was statistically significant(P <0.05).The incidence of chest pain and weight loss of type ? was higher than that of type ?,but there was no significant difference(P> 0.05).9.There was no significant difference in IRP,LESP and LESL between type ? and(P> 0.05),DEP of type was significantly higher than type(P <0.05).? ? ?10.In addition to conservative treatment,there were statistically differences in the composition between balloon dilatation and surgical cardia resection(P<0.05).Conclusions:1.Peak age of men and women are middle and old age,the age of illness is unrelated with the sex.2.Emotional,mental stress may be the incentive of AC,but maybe there is no clear incentive in AC.Smoking,drinking may not be a risk factor for AC.3.Dysphagia and reflux are the main manifestations of AC,dysphagia,nausea and vomiting appear more easily in the male.4.Gastroesophageal reflux disease was the most common in esophageal-related disease of AC.5.Gastroscope examination is easy to miss diagnosis of achalasia.6.The whole esophagus high pressure during swallowing may not be a reason for dysphagia and chest pain in patients with achalasia.The whole esophagus high pressure during swallowing may prevent reflux.7.Distal esophageal pressure of AC is correlation with reflux symptoms,patients with strong distal esophageal pressure is not prone to reflux.8.The conservative treatment and cardia balloon surgery are widely used in clinnical treatment of achalasia. |
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