To Observe The Dispersing Stagnated Liver-qi On Irritable Bowel Syndrome (IBS) And The Result Of Intestinal Flora Regulation

Objective:aiming to observe the dispersing stagnated liver-qi on diarrhea predominant irritable bowel syndrome(IBS-D)and the effect on intestinal flora regulation.Methods:63 IBS-D patients,had be randomly divided into 2 groups.The drug-thread group of 33 patients;the control group of 30 patients;Experiment group was treated with Tong Xie Yao Fang combined with Si Ni San,control group was treated with oral of Pinaverium Bromide.Patients took One courses of treatment.four weeks were a course.Symptoms and total effective rate and Intestinal flora status were observed in the 4th week after the treatment process.Conclusions:1.In the 4th week,and the symptoms of treatment group and control group of two groups of patients before treatment is improved,the total effective rate of treatment group was 96.97%,control group total effective rate was 80.00% in the treatment group compared with control group,P<0.05,there was statistical significance2.In symptom score respect,abdominal discomfort,stool frequency,stool,defecation urgency score,treatment group and control group in the 4th week,P<0.05,they were of statistical significance,indicating that the treatment group in the 4th week of defecation frequency,stool curative effect were better than pinaverium bromide group.Symptom score,the treatment group and the control group for the 4th week were P > 0.05,they were of no statistical significance.3.Two groups of patients after the treatment of anxiety score score comparison,P<0.05 was statistically significant.Two groups of patients after treatment,the score of quantitative comparison of depression,P>0.05,no statistical significance.The treatment group on anxiety is better than pinaverium bromide group.4.In respect of improving the intestinal flora(Escherichia coli,Lactobacillus,Bifidobacterium),the treatment group before and after treatment in each group of samples P<0.01,the difference was statistically significant.Conclusion:According to the clinical trial,Si Ni San combined with Tong Xie Yao Fang in treating diarrhea type irritable bowel syndrome,can improve patients symptoms with abdominal pain,defecation,stool,defecation urgency and other symptoms and their effects on intestinal microflora;Si Ni San combined with Tong Xie Yao Fang group curative effect is better than the pinaverium bromide group,toxicity was not found in the process of treatment,four inverse scattered and Si Ni San combined with Tong Xie Yao Fang prescription safety,treatment of diarrhea type irritable bowel syndrome is effective,worthy of further study.