The Clinical Value Of D-dimer In Hepatic Cirrhosis Patients

Objective: Explore D-dimer level and its clinical significance in patients with hepatic cirrhosis,and whether D-dimer level in different child-pugh classification have differences.Method: We picked out the ones who had diagnosed hepatic cirrhosis and hospitalized from January 2015 to December 2016 in our hospital,and texted D-dimer,totally235.count the related biochemical indicators,and analyzed retrospectively?We divided the patients into the child class A(group A),the child class B(group B)and the child class C(group C)according the child-pugh score.Using T test in comparing different groups' plasma D-dimer,cholinesterase,albumin,blood calcium,cholesterol,platelets,and prothrombin time,total bilirubin,alkaline phosphatase,AFP levels?Results 1.with the grading of Child-pugh classification increasing,D-dimer,total bilirubin and prothrombin time increased in serum of patients with liver cirrhosis,the differences in group B and group A,group C and group B are statistically significant(P < 0.05).2.As the child grades increased,serum cholinesterase,albumin,blood calcium,cholesterol levels gradually declined,the differences in group B and group A,group C and group B are statisticallysignificant(P < 0.05).But to Alkaline phosphatase,AFP,platelet,there was no statistically significant difference between the three groups(P >0.05).Conclusions: In patients with hepatic cirrhosis,D-dimer rised which is related to the impairing degree of the hepatic function,namely the more severely liver function damaged,the more obviously D-dimer rised.D-dimer level can be used to judge the prognosis of liver disease.In clinical,conjunction with other relevant biochemical indicators could assess the liver damage degree more accurately,and provide important reference significance to the corresponding diagnosis and treatment.