| According to the American Psychiatric Association's Mental Disorders: Diagnostic and Statistical Manual of Mental disorders-IV(DSM-IV),insomnia can be divided into primary insomnia(PI)and secondary insomnia in terms of etiology.PI is more common seen in the clinical.Anxiety,depression and other mental disorders often associated with insomnia.Objective:To explore the clinical characteristics and cognitive impairment of PI patients,to understand the co-disease situation between PI and anxiety,depression.Methods:Continuous selection of September 2016 to November 2016 in Beijing Haidian Hospital neurology outpatient treatment of PI patients 229 cases,and recorded baseline indicators.Include:sex,age,body mass index(BMI),education level,whether of long-term drinking,etc.At the same time,doing anxiety,depression,cognitive function scale evaluation.According to different criteria,229 PI patients were divided into short-term insomnia group and chronic insomnia group according to ICSD-3 insomnia diagnostic criteria.Secondly,according to age,sex and symptom grouping,to further compare the patients with anxiety and depression and cognitive function.Results:1?In 229 PI patients,the mean age was 49.69 ± 16.385 years(18 to 80 years).Including 87males(38%),142 females(62%);57 cases of short-term insomnia(24.9%),172 cases of chronic insomnia(75.1%).;94 cases of sleep difficulties(41.0%),47 cases of early awake(20.5%),43 cases were difficult to maintain(18.8%),mixed in 45 cases(19.7%).2?The incidence of anxiety and depression in short-term insomnia group was not significantly different from that in chronic insomnia group(P> 0.05).The scores of MoCA scale and visual function were significantly higher in the short-term insomnia group than those in the chronic insomnia group(P <0.05).There was significant difference in the incidence of cognitive impairment between short-term insomnia group and chronic insomnia group(P <0.05).3?There was no significant difference in the score of anxiety between the elderly PI group and the non-elderly PI group(P> 0.05).There was significant difference in the score ofdepression between the PI group and the non-elderly PI group(P <0.05).There was no significant difference in the incidence of anxiety between the elderly PI group and the non-elderly PI group(P> 0.05).The difference of the incidence of depression between the elderly PI group and the non-elderly PI group was statistically significant(P <0.05).4?There was no significant difference between male PI group and female PI group in the scores of anxiety and depression scores and the incidence of anxiety and depression(P> 0.05).There was no significant difference between the male PI group and the female PI group in the overall cognitive function score and the incidence of cognitive impairment(P> 0.05).Among them,the scores of male PI group and female PI group in delayed recall function The difference was statistically significant(P <0.05).5?There were significant differences in depression scores between the four groups(P<0.05),The scores of HAMD scores among the four groups were: mixed symptom>maintenance>early awakening>difficulty in falling asleep.Conclusion:1?In PI,non-elderly accounted for a larger proportion.Chronic insomnia more common,the number of women more than men.Clinical manifestations are difficulty falling asleep,early awake and so on.2?Short-term insomnia and chronic insomnia combined with anxiety and depression were no significant differences,but the probability of chronic insomnia combined with cognitive decline was higher than short-term insomnia.3?Non-elderly PI patients were more likely to develop depression than older PI patients.4?Male PI patients in the delayed recall than female PI patients decreased significantly.5?PI patients with early awakening,sleep maintenance difficulties,or mixed symptoms are more likely to be associated with depression. |
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