The Effects Of Progressive And Rapidly On The High Altitude Of Physiological And Psychological Of Chinese Antarctic Pre-expeditioners-the Research Of The 31^st,32^nd,33^rdChinese Antarctic Pro-expeditioners Of Kunlun Station

Background The high altitude environment is characterized with low pressure,hypoxia,coldness,dry,and intense ultraviolet radiation.When lowlanders ascend towards high altitude rapidly,they could easily develop acute mountain sickness(AMS).Everybody has different feelings and tolerances of hypoxia,there is no specific examination can directly screen out the susceptible population of high altitude disease,but can be used to directly estimate the method of screening for hypoxia susceptible people.Through the long-lived plains quickly into the plateau,the detection of human hypoxia-sensitive vital organs of the system to adapt to changes in function,to rule out hypoxia susceptible population.Cardiovascular system and respiratory system are sensitive to the ambient oxygen content,thus,the changes of cardiac and pulmonary function play an important role in human adaptation under high altitude environment.Different altitudes affects mood states differently.Human mood began to change since they arrive 4000 m,and its features and severity are associated with severity and duration of hypoxia.The mood changes are also associated with hormone levels.Chinese Kunlun Station is located at inland plateau with an altitude of 4093 m and harsh natural environmental factors.In recent years,China Antarctic Dome Argus scientific expedition will gradually replace the snowmobile with the fixed-wing aircraft to transport expeditioners and materials from Zhongshan station to Kunlun station,so for the selection of qualified expeditioners and the development of medical control measures,the researches of different physiological and psychological impacts of the Kunlun station pro-expeditioners progressive and rapid advance of the plateau have practical significance.Methods According to their transportation ways towards high altitudes,the subjects were divided into the train crew(N=30)and the airplane crew(N=55).We analyzed the physiological and psychological changes of the two crews at the three time points:the sea level(Shanghai),arriving at 3650 m(Lhasa)in 24 h,arriving at 4300 m(YangBajing)in 24h.We evaluated the mood and sleep via questionnaire and monitored the physiological changes of subjects via electrocardiogram(ECG),cardiac function device,and pulmonary function device.We collected saliva and measured salivary testosterone,cortisol and Immunoglobulin A(IgA).In addition,we monitored oxygen saturation of the subjects and evaluated their AMS symptoms to compare the effects of two transportation ways on physiological and psychological changes.Results Compared to the sea level value(4 m),the physiological and psychological parameters of airplane crew and train crew changed significantly.Compared to the train crew,the physiological and psychological parameters of airplane crew changed significantly:the negative mood scores increased,the EEG disorders increased,the cardiac and pulmonary function changed,thoracic fluid content(TFC)increased at 4300 m,salivary testosterone and IgA reduced.For the train crew,the change value of TFC was positively correlated with salivary IgA.It suggesting that testosterone can be used as a plateau hypoxic environment on the physiological and psychological impact of the observed indicators.Conclusion The train crew(gradual ascend)and airplane crew(rapid ascend)both performed significantly changes in physiology and psychology under hypoxia environment,while compared with train crew the airplane crew had more significantly changes.