Observation Of Intravitreal Triamcinolone For Macular Edema Induced By Ischemic Central Retinal Vein Occlusion In Uighur

Object This study is aimed to investigate the clinical efficacy of intravitreal triamcinolone for macular edema induced by ischemic central retinal vein occlusion and discuss the efficacy and safety of intravitreal triamcinolone for the Uygur patients in Kashi district.Methods Choose 60 patients of macular edema induced by ischemic central retinal vein occlusion whose best corrected visual acuity is less than or equal to 4.0 from Uygur patients in Kashi district.At the first visit,no neovascularization of the retina or anterior segment was shown in all patients.60 patients then were divided into experimental group and control group,each group with 30 patients.Triamcinolone acetonide intravitreal injection was performed in patients of the experimental group.For which intraocular pressure measurement,best corrected visual acuity(BCVA),examination of anterior segment and fundus,fluorescein angiography(FFA)and optical coherence tomography(OCT)and central macular thickness(CMT)were also performed before and after the treatment.Postoperatively,the patients were followed up for at lease 6 months,whether there is any adverse reaction were observed during this period.Results At the 1st,3rd and 6th month of the follow-up period:in the experimental group,BCVA was improved in 26 eyes,25 eyes,24 eyes respectively,which was significantly higher than 11 eyes,11 eyes,10 eyes in the control group(?2= 15.87,P <0.01;?2= 13.57,P <0.01;?2= 13.32,P <0.01),the difference was statistically significant.with the OCT examination,in the experimental group,macular edema was regressed in 24 eyes,24 eyes,23 eyes respectively,which was significantly higher than 10 eyes,10 eyes,8 eyes in the control group(?2= 13.32,P <0.01;?2= 13.32,P <0.01;?2= 15.02,P <0.01),the difference was statistically significant.with FFA examination,in the experimental group,retinal vascular permeability reduced and macular edema was regressed in 27 eyes,26 eyes,25 eyes respectively,which was significantly higher than 13 eyes,11 eyes,8 eyes in the control group(?2= 14.72,P <0.01;?2= 15.87,P <0.01;?2 = 19.42,P <0.01),the difference was statistically significant.in the experimental group,no adverse reaction was observed after intravitreal triamcinolone,and during the follow-up complication rate was 20.0%,which was 13.3% in the control group(?2=0.480,P=0.488),there is no statistical difference.Conclusion TA therapy can significantly reduce macular edema induced by ischemic CRVO,release the retinal ischemia and improve visual function,which achieved good clinical results.IVTA treatment has a low complication rate amd excellent safety.