| Objective: Through the acute myocardial infarction in patients with emergency PCI before the application of salvianolate,after the opening of infarct related artery count corrected TIMI frame count assessment of coronary flow,effects of changes in the changes of ST segment and R wave amplitude in ECG-related leads before and after treatment of infarct-related arteries on myocardial ischemia-reperfusion injury,to explore the treatment of ischemic-reperfusion injury in patients with acute myocardial infarction.Methods: From January 2016 to December 2016,80 patients with acute ST-segment elevation myocardial infarction were diagnosed by cardiovascular surgery,and the onset time is shorter than 12 hours,were randomly divided into test group and control group,all the patients in the group were treated with aspirin 300 mg and Grillo 180 mg,test group in the conventional oral drug based on the addition of salvianolate 200 mg static point.Respectively,in the infarct-related artery balloon open immediately,5 minutes after the opening,10 minutes after the opening count of coronary artery blood flow to the distal branch of the corrected TIMI frames,5 minutes before the opening of the infarct-related artery balloon,5 minutes after the opening,10 minutes after the opening of the ECG-related lead ST segment and R wave amplitude changes,the above-mentioned monitoring indexes were analyzed statistically in different groups of patients and between the two groups,and the differences were compared.Results:1 The two groups of patients with baseline indicators,namely age,infarction related artery opening 5 minutes before the ST elevation,R wave amplitude and the patency of infarct related arteries immediately after correction of TIMI frames without statistical differencenamely(P> 0.05).2 In the control group,the infarct-related arteries were immediately,5min and 10 min,respectively.The ST-segment elevation values were(0.3580±0.06354)mv,(0.3343±0.06827)mv,(0.3320±0.06888)mv,the amplitude of R wave is(1.4353±0.20666)mv,(1.4010±0.19525)mv,(1.3720±0.18582)mv,were not statistically significant(P>0.05).The infarct related artery after the opening 5 minutes and 10 minutes respectively,corrected TIMI frame count(30.2625 + 5.62844)frame,(29.5500 + 5.79434)frame,suggesting that infarct-related arteries after 5 minutes,10 minutes compared with the baseline were statistically significant(P<0.05),but 5minutes after the opening of the infarct-related artery and 10 minutes after the opening was not statistically significant(P>0.05).3 In the test group,the infarct-related arteries were immediately,5 min and 10 min,respectively.The ST-segment elevation values were(0.3522±0.06233)mv,(0.3203±0.06538)mv,(0.2695±0.07531)mv,suggesting there was no statistically significant difference between the prompts and the baseline(P> 0.05),5 minutes after opening,10 minutes and the baseline and immediately after the opening were statistically significant(P< 0.05),10 minutes after opening and 5 minutes after opening compared to still statistically significant(P<0.05).The amplitude of the R wave is(1.3875±0.18403)mv,(1.3838±0.18422)mv,(1.3810±0.18282)mv,were not statistically significant(P> 0.05).The infarct related artery after the opening 5minutes and 10 minutes respectively,corrected TIMI frame count(27.1125±4.72512)frames,(24.4125±5.00242)frames,suggesting that 5minutes after the opening of the tips,10 minutes and the baseline were statistically significant(P<0.05),5 minutes after opening and 10 minutes after opening compared to still statistically significant(P<0.05).4 Contrast between groups,compared the control group with the test group,the ST segment elevation value of the control group was statistically significant at 10 minutes after the infarct-related artery was opened(P<0.05),other time periods were not statistically significant(P >0.05),there was no statistically significant difference between the R wave amplitude group andthe control group(P>0.05),the corrected number of TIMI frames was statistically significant at 5 minutes after opening and 10 minutes(P<0.05).Conclusion:1 Salvianolate can effectively inhibit myocardial ischemia-reperfusion injury,onset time early,and with the increase in profitability over time.2 Salvianolate can improve coronary microcirculation perfusion. |
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