Objective:To observe hemostatic effect and investigate the hemostatic mechanism preliminarily of Gongxue Liting Decoction?GXLTD?in treating Metrorragia and Metrostaxis with Qi Deficiency and Blood Stasic Syndrome,provide a theoretical basis for this study,and provide the basis for TCM treatment of uterine bleeding.Methods:60 patients were divided randomly into treatment group and control group.Observation of clinical symptoms and signs of improvement,serum Ca2+level,prothrombin time?PT?and activated partial prothrombin time?APTT?to compare differences between the two groups.Results:The treatment group and the control group hemostatic effect of total effective rate were 90%and 63.33%,the two groups have Significant difference?P<0.05?;the curative effect of TCM syndrome improvement,the total efficiency of the two groups were 93.33%and 66.67%,the difference was statistically significant?P<0.05?;compared with before treatment,there was significant difference between the two groups in the prothrombin time?PT?and activated partial prothrombin time?APTT?,elevated serum Ca2+levels?P<0.05?,and there was significant difference between the treatment group and the control group after treatment?P<0.05?.Conclusion:GXLTD has good hemostatic effect on Metrorragia and Metrostaxis with Qi deficiency and blood stasis syndrome,and can improve the symptoms,the hemostatic mechanism may be a number of links through the regulation of blood coagulation and fibrinolysis system,improve the level of serum Ca2+to enhance coagulation function,and strengthen uterine smooth muscle contraction,act on improve endometrial microcirculation,promote endometrium abscission to reflect. |