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The Application Analysis Of Low Temperature Plasma Ablation In The Treatment Of Inverted Papilloma Of The Nasal Sinus And Sinuses

Posted on:2019-02-16Degree:MasterType:Thesis
Country:ChinaCandidate:X H YangFull Text:PDF
GTID:2334330545989545Subject:Otolaryngology
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BackgroundNasal inverted papilloma(NIP)is a common intranasal benign tumor.The age of onset is usually between 50 and 70 years old.The number of people in the male population is higher than that in the female population.The nasal congestion,intranasal mass,and nasal discharge Bloodshots,frontal sinusitis,or nasal bleeding are often accompanied by headaches,facial pain,and olfactory failure.At present,the main treatment of NIP is surgical treatment.Endoscopic surgery has many advantages over open surgery and has been widely promoted.Endoscopic low-temperature plasma ablation is a new type of minimally invasive treatment of NIP developed in recent years.Surgical methods.ObjectiveTo compare the efficiency of surgical resection of NIP resection with the use of endoscopic low-temperature plasma ablation and electric cutting under nasal endoscopy,the time taken for surgery,the amount of intraoperative blood loss,postoperative pain,and postoperative nasal mucous membrane recovery.,Postoperative recurrence,and the incidence of postoperative complications,etc.,to screen out more safe and effective surgical treatment of NIP.MethodsThis study selected 61 patients with nasal cavity and paranasal sinus prolapsed papilloma from August 2011 to July 2015.All patients met the inclusion criteria and did not meet the exclusion criteria.According to the patients'surgical procedure,the patients included in the study were divided into two groups,plasma combined electric cutting group,in which plasma group patients underwent endoscopic low-temperature plasma ablation,and electric cutting group underwent endoscopic electric cutting.Comparing the two groups of patients,the efficiency of surgery,the time used for the operation,the amount of intraoperative blood loss,postoperative pain,postoperative nasal mucosa recovery,recurrence within two years after surgery,and the incidence of postoperative complications and other differences.ResultsTotal effective rate:There was no significant difference between the total effective rate of stage I patients in the plasma group and patients in stage I of the electrokinetic group(X~2=6.084,P=0.062).The total effective rate of stage II and stage III patients was significantly higher than that of the patients with electrocution(X~2=7.425,P=0.032;X~2=10.426,P=0.000).Operation time:There was a significant difference in the operation time between patients in the plasma group(F=28.491,P=0.028);the operation time in patients with stage I,II,and III in the electrokinetic group was significantly higher than that in the plasma group(t=6.362,P=0.000;t=10.489,P=0.000;t=2.937,P=0.043).There was a significant difference in the operation time between the three phases(F=38.319,P=0.014).Intraoperative blood loss:There was a significant difference in intraoperative blood loss between patients in the plasma group(F=59.310,P=0.035).The intraoperative blood loss in the patients with stage I,II,and III in the electrocution group was significantly higher than that in the plasma group(t=11.267,P=0.000;t=12.643,P=0.000;t=8.362,P=0.000).There was a significant difference in intraoperative blood loss between the three patients(F=83.234,P=0.025).Postoperative mucosal epithelialization time:There was a significant difference in the duration of postoperative nasal mucosal epithelialization between patients in the plasma group(F=54.232,P=0.021);there was no significant difference in postoperative nasal mucosal epithelialization time between the patients with electrocution and the plasma group(t=2.382,P=0.095),both in stage II and stage III were significantly higher than those in the plasma group(t=24.382,P=0.028;t=42.298,P=0.017).There was significant difference in the duration of nasal mucosal epithelization between the three groups of patients.Difference(F=42.392,P=0.016).Recurrence rate:The postoperative recurrence rate was higher in the electrokinetic group than in the plasma group(X~2=8.239,P=0.003).The incidence of postoperative complications:There was no significant difference in the incidence of symptoms such as postoperative nasal hemorrhage,nasal infection,adhesion,vision loss,nasolacrimal duct damage,and poor sinus drainage in the plasma group(X~2=1.404,P.=0.185;X~2=1.404,P=0.185;X~2=1.060,P=0.106;X~2=1.060,P=0.106;X~2=1.404,P=0.185);The incidence of complications in the electrokinetic group was significantly higher than that in the plasma group.Patients(X~2=3.857,P=0.037).ConclusionsEndoscopic cryoablation and contrast endonasal wound surgery have less bleeding,shorter operative time,shorter mucosal epithelialization time,higher postoperative effective rate,and low recurrence rate.The advantages of less complications are a safe and effective surgical approach to treat NIP.
Keywords/Search Tags:Endoscope, low-temperature plasma ablation, Traditional endoscopic excision, Nasal sinus inversion papilloma
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