| Research Purpose Observe the clinical efficacy using Yi-kun-kang-shuaitang which is created by Professor Zhang Jin-feng and Climen(Complex packing Estradiol Valerate Tablets,Estradiol Valerate and Cyproterone Acetate Tablets)treat POF.And explore its mechanism of action.Research Methods Random Grouping 60 POF patients strictly in accordance with the inclusion criteria and exclusion criteria.Chinese and Western medicine treatment group uses Yi-kun-kang-shuai-tang and Climen(Complex packing Estradiol Valerate Tablets,Estradiol Valerate and Cyproterone Acetate Tablets).Western medicine control group uses Climen(Complex packing Estradiol Valerate Tablets,Estradiol Valerate and Cyproterone Acetate Tablets).And Chinese medicine control group uses Yi-kun-kangshuai-tang.The treatment lasted for three months.After treatment,observe the patients for three months.The objects need observe include the curative effect of TCM syndrome,the improvement of TCM syndromes,the improvement of total score of TCM,the change of total score of TCM syndromes,the change of sex hormone level,the thickness of endometrium and the size of ovary Variety etc.And Blood routine,urine routine,coagulation routine,liver function,renal function,electrocardiogram,uterus and bilateral accessories color Doppler ultrasound,bilateral breast ultrasound also need observe.All the data were analyzed by SPSS16.0 software,and the results were based on the statistical results.Conclusion Using Yi-kun-kang-shuai-tang and Climen(Complex packing Estradiol Valerate Tablets,Estradiol Valerate and Cyproterone Acetate Tablets)treat POF have exact effects.It can Can improve POF patients with irregular menstruation,improve TCM syndrome points,reduce the symptoms of Yaoxisuanruan,lower FSH levels,LH levels,increased E2 levels,increased endometrial thickness.This treatment is Effective,safe,and worthy of further clinical research and promotion. |
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