Purpose:By eliminating phlegm blood particles(meridian)in the treatment of stroke recovery wind phlegm and blood stasis resistance research of syndrome,observe the clinical efficacy and safety of expectoranting blood particles.Material and method:Research object is selected in September 2016-March 2017 in liaoning university second affiliated hospital of traditional Chinese medicine,Pu Lan Dian hospital,jinzhou city hospital,donggang hospital outpatient and ward of 32 cases of stroke(meridian)in convalescence wind resistance syndrome in patients with phlegm and blood stasis.By using the random number table method,according to the proportion of 1:1,divided into expectoranting blood particles in test group and aspirin group,16 cases in each group,according to the order of subjects into groups and drug coding sequence in the dispensing of growing up.Expectoranting blood particles group,1 bag,three times a day orally,use 4weeks;Aspirin in the control group,100 mg,an oral,4 weeks.In the preparation before-3-0days and 28 + /-3 days after each do an experiment examination,routine blood,urine routine,and routine,electrocardiogram(ecg),liver function,renal function,hemorrheology,adverse reactions and adverse events as a safety measure,to assess the expectorant blood grain security.In medicine and drugs-3-0 days before 28 + /-3 days after each observation recording an NIHSS score and TCM syndrome score,and make statistical processing,to assess the clinical curative effect of expectoranting blood particles.Results:1.The balance between the two groups: two groups of patients in terms of gender,age distribution has no obvious difference(P > 0.05),that was comparable between the two groups;Comparison between the two groups before treatment NIHSS score points groups,no significant difference(P > 0.05),and that was comparable between the two groups;The two groups before treatment of TCM syndrome score points is compared between group,no significant difference(P > 0.05),and was comparable between the two groups.2.Results:NIHSS score points for the two groups after treatment compared with before their treatment,there were significant differences(P < 0.05),the NIHSS score points for the two groups after treatment than before treatment were lower;Treatment group after treatment compared with the control group after treatment NIHSS score curative effect between groups,there were significant differences(P < 0.05),explain in general curative effect,experimental group is better than the control group.The two groups after treatment of TCM syndrome score points compared with before their treatment,there were significant differences(P < 0.05),the two groups after treatment of TCM syndrome score points before treatment were lower;Experimental group and the control group after treatment the curative effect of TCM syndrome score after treatment group comparison,there were significant differences(P <0.05),explain in general curative effect,experimental group is better than the control group.3.Security measure:Observe patients through safety testing,blood routine,urine routine,and routine,electrocardiogram(ecg),liver function,renal function,hemorrheology,medication during the presence of adverse events and adverse reactions,display during treatment with expectoranting blood particles no adverse reaction occurred,no interruption of treatment because of the serious adverse events.Conclusion:Expectoranting blood particles can improve stroke(meridian)in convalescence wind phlegm and blood stasis resistance syndrome in patients with clinical symptoms,reduce spit blood particles reliable curative effect,no adverse reactions during treatment with expectoranting blood particles and adverse events. |