Study On The Effects Of Air Pollution On The Death Of Cardio-cerebrovascular Diseases In Shijiazhuang City

Objectives Air pollution is one of the major public health problems in the world,which can caused adverse effect on human's health.Cardio-cerebrovascular disease is a high incidence disease in our country,ranking first in the cause of death.The study analyzed the relationship between the death of cardio-cerebrovascular and the concentration of air pollutants in Shijiazhuang city,to understand the delayed effect,dose-response relationship and seasonal difference of air pollution to the mortality of cardio-cerebrovascular diseases.Methods Collection daily deaths of cardio-cerebrovascular disease,meteorological factors?temperature,relative humidity,air pressure?,and air pollution(particulate matter with an aerodynamic diameter less than 10?m[PM10],air pollution(particulate matter with an aerodynamic diameter less than 2.5?m[PM_2.5],sulfur dioxide[SO₂],nitrogen dioxide[NO2]and ozone[O3])from 1 January 2014 to 31 December 2016 in Shijiazhuang city.Distributed lag non-linear models and generalized linear models were used to evaluate the relationship between the deaths of cardio-cerebrovascular disease and ambient air pollution.SPSS software were used to correlation analyzed,R Studio were used to time series analyzed.Results 1 The analysis shows that the concentration of air pollutants is related to the death of cardio-cerebrovascular diseases,which shows that the concentration of pollutants increases the death of cardio-cerebrovascular diseases,and there is a lag effect.The analysis of single contaminant model shows that,after the increase of the pollutant concentration,the influence on the residents increases gradually with the increase of the lagging time.However,the increase of pollutant concentration in the day had no effect on the mortality of the residents.The lagged effect of PM_2.5and PM₁₀was the largest in the third day after the increase of concentration,and the effect value was 0.43%?95%CI:0.20%-0.66%?and 0.34%?95%CI:0.19%-0.49%?.For SO2 and NO2,there was a maximum lag effect of 0.71%?95%CI:0.21%-0.86%?in the lag of 4 days?95%CI:0.35%-0.17%?.O₃ increased the risk of excess mortality by 0.56%?95%CI:0.18%-0.94%?at the time Lag1 when the concentration increased by 10?g/m³.In the multi-pollutant model,after adjusting other factors,the effects of other pollutants were statistically significant except O₃.2 According to the stratification of heating season/non-heating season,the death effect of heating season is higher than that of non-heating season.During the heating season,when Lag3 days,the PM_2.5concentration increased by 10?g/m³,and the risk of death from cardiovascular and cerebrovascular disease was 0.67%?95%CI:0.48%-0.86%?.For every 10?g/m³ increase in PM₁₀concentration,the excess risk of cardiovascular death increased by 0.35%?95%CI:0.14%-0.58%?.The average daily concentration of SO₂increased by 10?g/m³,and the ER was 1.08%in Lag4 days?95%CI:0.77%-1.38%?.The lagged effect of NO2 was the largest in Lag4 days,and the average daily concentration increased by 10?g/m³,resulting in an increase of 1.06%?95%CI:0.38%-1.78%?in the deaths of residents.In the non-heating season,only increased O₃ concentration could lead to a 1.25%increase in the death rate of cardio-cerebrovascular disease?95%CI:0.93%-1.58%?in Lag1 days.3 The effect of PM_2.5on the elderly is lagging behind.Both PM_2.5and PM₁₀0 have the maximum effect of Lag3 days,respectively 0.90%?95%CI:0.69%-1.12%?and 0.59%?95%CI:0.44%-0.74%?.For every 10?g/m³ increase in SO₂concentration,the maximum risk of excess mortality was 1.18%?95%CI:0.63%-1.74%?when Lag3 days.The maximum effect of NO₂ was 2.45%?95%CI:2.23%-3.00%?after 3days of lag.All the pollutants showed that the increase of the day's concentration had no statistically significant effect on the death of cardio-cerebrovascular diseases.Conclusions 1 The increase of air pollutant concentration in Shijiazhuang city can increase the death risk and lag effect of cardio-cerebrovascular diseases in the residents.2The effects of air pollutants on the health of cardio-cerebrovascular diseases have obvious seasonal differences,and the effect value in the heating season is greater than that in the non-heating season.3 The elderly are vulnerable people affected by air pollution.