Construction And Test Of The Joint Platform Of Optically Detected Magnetic Resonance And Optical Tweezers

Organisms are rich in spins that can generate magnetic signals,and various life activities are often accompanied by the generation or change of magnetic signals,such as the conduction of neural signals.For this reason,it is of great scientific significance to measure the magnetic signal in the organism at the micro scale,which can deepen our understanding of some life phenomena.Traditional MRI,which can be used for in vivo magnetic detection,can only measure millimeter scale ensemble samples,and cannot detect single cell or even single molecular scale microscopic objects.In recent years,the newly developed technology of optically detected magnetic resonance,using the nitrogen-vacancy center(NV center)in diamond as a quantum sensor,can be used not only for living cells,but also for single molecular magnetic resonance.At the same time,NV center can exist stably in nano diamond,which has low cytotoxicity and can enter living cells.Combined with the technology of optical tweezers,which is of high-precision space control,NV center is the most promising method for single molecular scale magnetic detection in living cells.Based on this experimental target,we set up a joint platform of optically detected magnetic resonance and optical tweezers.In the first chapter,we briefly introduce the development background of the technology of optically detected magnetic resonance and optical tweezers;in the second and third chapters,we respectively explain the principles of the two technologies and the construction of the platform;in the fourth chapter,we mainly describe some tests on the joint platform;in the last chapter,we summarize the construction of the platform and look forward to the future experiments.