Study On The Preparation Of Two-and Zero-Dimensinal Carbon Nanomaterials And Their Application In Non-Enzymatic Glucose Sensors

Blood glucose concentration is an important indicator of many diseases such as diabetes and endocrine metabolic disorders.Accurate,rapid,sensitive and careful monitoring of glucose concentration is of great significance for the diagnosis and treatment of related diseases.The non-enzymatic glucose sensor has the characteristics of low cost,wide linear range,high sensitivity and fast response,and is a hot topic in the field of biosensors.Furthermore,material of electrode is of vital importance to the performance of sensor.Graphene,as a kind of electrode material,has a high specific surface area,high mobility and low noise,and the structure contains a large number of defects and a wealth of functional groups.In the meantime,as a kind of carbon dots,graphene quantum dots have large specific surface area,rich edge position and inherent catalytic activity.The introduction of these two carbon materials facilitates the improvement of electrochemical sensing performance.This paper describes the synthesis methods,physical and chemical properties of these two carbon materials and their related work in the field of non-enzymatic glucose sensors.With the electron transfer ability and active site as the measurement standard of electrochemical performance,the properties of graphene and graphene quantum dots as carriers of non-enzymatic glucose electrochemical biosensors were investigated from these two perspectives.The specific research content is as follows:Firstly,the preparation of the flake graphite was achieved via the top-down synthesis route.Through the structure and morphology analysis,it was found that graphene oxide has a lower degree of disorder and less oxygen-containing functional groups than graphene quantum dots.Secondly,a simple and rapid microwave hydrothermal method was applied to synthesize the cuprous oxide/graphene and cuprous oxide/carbon dot composites.The results show that cuprous oxide/redox graphene has better glucose catalytic performance and smaller charge transfer resistance.And through electrochemical data analysis,GO has a smaller charge transfer resistance,and GQDs have weak current response to glucose.Finally,based on the results of the previous chapter,graphene as a conductive bridge for electron transfer is more conducive to the improvement of glucose sensitivity.Through the three-dimensional graphene structure,the interface structure of the composite material was adjusted to optimize glucose-sensitive properties.It is proposed that three-dimensional graphene-coated copper cobalt oxide is obtained by hydrothermal,etching and calcining methods.Experiments show that the material has better sensitivity,lower detection limit and good anti-interference.