Construction And Functional Design Of Fluorescence Probes For Detecting Biological Molecule And Inorganic Ionic Based On Lanthanide MOF

Among the classes of porous materials,metal-organic frameworks?MOFs?attract unparalleled attentions in their degree of structural designability and pore size tunability.Around the mainly focuses of lanthanide metal-organic framework?Ln-MOFs?in this paper,four system of Ln-MOF were synthesized based on polycarboxylic acid ligand 5,5',5''-[?1,3,5-triazine-2,4,6-triyl?tris?oxy?]triisophthalic acid and 4,4',4''-[?1,3,5-triazine-2,4,6-triyl?tris?sulfanediyl?)tribenzoic acid)under hydrothermal or solvothermal conditions.Based on the advantages of the structure and fluorescence properties of each system Ln-MOF,the above-mentioned Ln-MOFs in fluorescence detection,such as metal cations,anions,solvent small molecules,and biological small molecules were intensively studied.The specific work is carried out as follows:1.Anewluminescentlanthanidemetal-organicframework[Tb?dpa^??·5H₂O]·solvent?H₂dpa^?=3,5-dicarboxy-phenol anion ligand?with millimeter-sized 2D network structure was synthesized.The as-synthesized Tb-MOFs exhibit a strong green luminescence.Importantly,the compound exhibits the ability of selective and ultra-high sensitive recognition on detecting Pb²⁺ion in aqueous solution.2.Based on the previous work,we present an innovative approach for synthesizing a novel luminescent probe by doping Tb³⁺and Eu³⁺into the same framework.The visible photoluminescence emission from red to green can be successfully adjusted by changing the excitation wavelength and controlling the molar ratio of Eu³⁺/Tb³⁺.The fluorescence of doped compound can be quenched by low water content and exhibit perfect linear correlation with the luminescence intensity,which can be utilized for potential luminescence ratiometric sensor for detecting traces water in ethyl alcohol.3.According to the theory of HSAB,a novel Ln-MOFs was successfully constructed,which exhibits strong green luminescence.Firstly,a novel three-dimensional structure of Zn-MOF was synthesized using the ligand H₃tsta under hydrothermal conditions.Furthermore,the Post-modification compounds are suitable for act as a highly selective and sensitive robust luminescent platform for reversibly detecting PO₄^3?in aqueous and living cell buffer solution with a fast response time and a very low detection limit.4.Based on the third part of the work,through the two-step modification,we report a creative“turn-on”fluorescent probe by utilizing Cu²⁺ion to adjust the fluorescence of Post-modification compounds for aspartic acid detection.More importantly,the IMPLICATION-type logic-gate and fuzzy membership functionwas built by the detection of Asp triggered fluorescent signal changed of MOFs recognition system.