The Structure Design Of An Artificial Bone Scaffold In The Middle Part Of Femur Based On 3D Printing

As an artificial bone graft material for bone defect repair,the internal structure and parameters of the scaffold have important effects on guiding bone and tissue regeneration.At present,The artificial bone scaffold layers exist in the structural design of the single,support performance improvement,thus proven support bones cell yuan pore shape and structure size on the mechanical properties,biological properties and the effect of combined with the characteristics of 3D printing stent structural design,can design produce to meet the requirements of actual medical framework to provide theoretical basis for artificial bones.Based on the analysis of the actual functional requirements and design standards of the artificial bone scaffold,this paper mainly considers the structural design of the bone scaffold from the two aspects of meeting the mechanical and biological properties of the bone scaffold.Firstly,the cellular structure of artificial bone scaffold is obtained by topological design and shape design of the object with maximum structural stiffness.The effect of cellular pore shape and structural size on mechanical and biological properties was analyzed,and the relation between compressive stress and permeability and structural size was obtained,and the cellular structure size of bone scaffold was obtained by combining with the improved particle swarm algorithm.Finally,according to the external contour of the middle segment of human femur and internal pore cells,the 3D model of artificial bone scaffold is established and converted into 3D printed data in STL format,which is manufactured by using SLA printer.Finally,through experimental analysis,the artificial bone bracket meets the actual functional requirements.Main research contents are as follows:1.Specific practical functional requirements and design standards of artificial bone scaffolds are analyzed to determine that the structural design requirements of bone scaffolds are suitable for mechanical properties(mechanical compressibility)and biological properties(including pore connectivity and biological permeability).So as to provide a basis for the structural design of artificial bone scaffolds.2.According to the topological design objective of maximum structural stiffness and the topology design and shape design of hexahedral structure with ANSYS software,the scaffold cell structure that meets pore connectivity and optimal stiffness performance can be obtained.3.The influence of cellular pore shape and structural size on mechanical and biological properties was analyzed.According to fluid mechanics simulation and mechanical analysis,the relationship between cellular permeability and compressive stress and structural dimension parameters was obtained respectively,and the permeability equation and compressive stress equation were derived.The pore size and permeability of cell were taken as the constraint parameters of size design.The compression stress of cell is taken as the target parameter of dimension design.The dimension of cell structure of bone scaffold is obtained by using the improved particle swarm algorithm.4.according to the human body the femur middle outer contour and the internal pore cell yuan individualized artificial bone scaffold three-dimensional model is established and converted to the STL format of 3D printing data,through pretreatment software Magics Link UnionTech to repair data and set up the printing layer parameters such as thickness,using SLA printer for 3D printing production,through the experimental analysis of artificial bone scaffold satisfies the requirement of practical function.In this paper,the effect of cellular pore shape and structure size of artificial bone scaffold on its mechanical properties(mechanical compressibility)and biological properties(biological permeability and pore connectivity)was studied.In addition,an artificial bone scaffold that meets the actual functional requirements and design standards is manufactured through 3D printing technology,providing a theoretical basis for the practical application of the artificial bone scaffold.