Synthesis And Properties Of Rare Earth And Transition Metal Sulfur-containing Schiff Base Complexes

The sulfur-containing Schiff base complex has magnetic,catalytic,antibacterial,luminescent and other properties,and has great application value in the fields of biological activity,catalysis,single molecule magnet,analytical chemistry and the like.The coordination of sulfur-containing Schiff base with metal ions can significantly improve its biological activity and enhance its application range.In this paper,four sulfur-containing Schiff base ligands were synthesized,and a series of complexes were synthesized with rare earth ions and transition metal ions.Their structures and biological activities were studied.The details are as follows:(1)The o-vanillin cysteamine hydrochloride ligand L~1 was synthesized from o-vanillin and cysteamine hydrochloride,and six rare earth complexes 1-6 were synthesized by solvothermal reaction with the nitrate of the lanthanide metal.Infrared,ultraviolet,thermogravimetric analysis,powder diffraction and single crystal diffraction were used to characterize it.Single crystal diffraction shows that the rare earth complexes 1-6 belong to the C2 point group and are octahedral monoclinic isomorphic complexes.(2)2-Hydroxy-1-naphthalene formaldehyde thiosemicarbazone ligand L~2 was synthesized by using 2-hydroxy-1-naphthaldehyde and thiosemicarbazide,and reacted with copper nitrate to form complex 7;using salicylaldehyde and thiosemicarbazide The salicylaldehyde thiosemicarbazone ligand L~3 was synthesized and reacted with nickel nitrate to form complex 8;ligand L~4 was synthesized with 2-formylphenoxyacetic acid and thiosemicarbazide,and nickel nitrate,cobalt nitrate and zinc nitrate were synthesized.The reaction produces complexes 9,10,and 11;salicylaldehyde cysteamine hydrochloride ligand L~5 is synthesized from salicylaldehyde and cysteamine hydrochloride,and reacts with nickel nitrate to form complex 12.It was characterized by infrared spectroscopy,ultraviolet spectroscopy,thermogravimetric analysis,powder diffraction and single crystal diffraction.The single crystal diffraction shows that the complex 7 belongs to the P2(1)/n point group and belongs to the monoclinic system,which is a four-coordinate one-dimensional chain copper complex;the complex 8 is a C2/c point group,which belongs to the monoclinic The crystal system is a mononuclear hexacoordinate nickel complex;the complex 9-10 belongs to the P21/c point group and belongs to the monoclinic system,and the complex 11 belongs to the P4/n point group and belongs to the tetragonal system;the complex 12 It belongs to the Pbca point group and belongs to the orthorhombic system.It is a trinuclear tetracoordinated nickel complex.The bioactivity of rare earth and transition metal complexes was tested by UV and fluorescence spectroscopy.The interaction with BSA/DNA was studied in a simulated physiological environment.The results showed that the quenching type of BSA/DNA was static quenching,and the calculated?G was less than 0,indicating that the interaction between the complex and BSA/DNA was spontaneous,and the rare earth and transition metal complexes and BSA/DNA has a strong binding ability and is of great significance for the synthesis of highly effective anti-cancer drugs with high toxicity and clinical application.In this paper,the photocatalytic hydrogen production test was carried out on the complex 12 of the complex 13 and the subject.The results show that the two Ni complexes have certain photocatalytic hydrogen production effects.