Study On Self-Assembly Behavior Of Amide Molecule By STM

Amide bond is-CO-NH-.The peptide bond is amide bond.It is benefit to further understand the assembly law of polypeptide and provide scientific basis for knowing the function of proteins by studying the self-assembly behavior of amide bond moleculae.On this basis,we selected a C₃ symmetric amide molecule benzene-1,3,5-tricarboxamides?ethyl cinnamate??BTAC?as the model.Its self-assembly behavior will be investigated at macro and micro scale.The contents of the study are as follows:1.BTAC molecule has been designed,synthesized and characterized.The self-assembly behavior of BTAC molecule was studied on macro-scale.The effects of solvent ratio on the self-assembled structure of BTAC will be investigated by scanning electron microscopy?SEM?,UV spectra and fluorescence spectra.As a control experiment,we then designed four organic-amino acid monomer molecules to investigate the microscopic morphology of the four amino acids at V_THF/V_H2O=3/7.The basic properties and assembly structure of tyrosine were characterized by several experimental methods,and the assembly structure was regulated by several factors.2.Study on self-assembly behavior of BTAC molecule by STM.STM technique will be used to study the self-assembly behavior of BTAC molecule on HOPG surface.In addition,the effect of solvent concentration was investigated.3.Regulation of guest molecules of self-assembly behavior of BTAC molecule by STM.STM technique will be used to study the effects of three guest molecules on the self-assembly behavior of BTAC molecules.It includes acid guest molecules?biphenyldicarboxylic acid and trimellitic acid molecules?and COR molecule.The self-assembly behavior of BTAC molecules is regulated by guest molecules.