Modified Sodium Alginate And Alkyl Glycoside Stabilized Drug-loading Emulsion And Regulate The Behavior Of Solution On Target Surface

Natural polymer is widely used in medicine,food,cosmetics and other industries due to the availability of raw materials,good biocompatibility and degradability.Alkyl glycoside?APG?,as a green nonionic surfactant,is also favored in many research fields because of its excellent surface activity.In this paper,the modified sodium alginate was prepared by a one-step chemical reaction method,and the effect of the complex of modified sodium alginate and APG on the stability of the pesticide water emulsion was studied.At the same time,the effects of the complex of modified sodium alginate and APG on the adhesion behavior,wetting behavior and evaporation performance of the solution on the target surface were also discussed.First,the effects of molecular weight,concentration,and p H on the stability of pesticide water emulsions were studied by visual inspection,multiple light scattering,optical microscope,rotational rheometer,differential scanning calorimeter,laser confocal microscope and microelectrophoresis apparatus.The results show that the high-molecular-weight sodium alginate derivative?H-Ugi-Alg?and APG complex and high-concentration H-Ugi-Alg and APG complex prepared bifenthrin oil-in-water emulsion with the highest stability.The high viscosity can inhibit the movement of droplets,reduce the collision probability of droplets,and can improve the stability of the emulsion to a certain extent.In addition,the steric hindrance provided by the emulsion droplet interface film and the electrostatic repulsion between the droplets are the main factors affecting the stability of the emulsion.Emulsions that are too acidic or alkaline are not conducive to its stability,and when the emulsion is in a weakly alkaline?p H=9?condition,the stability of the emulsion is optimal due to the electrostatic repulsion between the droplets.Secondly,in order to study the pesticide delivery efficiency of the pesticide oil-in-water emulsion,we studied the wettability and adhesion of the diluted pesticide oil-in-water emulsions on the surfaces of banana leaf by fully automatic surface tensiometer,optical contact angle/surface tension meter,gas chromatograph and fluorescence microscope.The results show that the wettability and adhesion of the H-Ugi-Alg/APG system solution on the surfaces of banana leaf are better than the M-Ugi-Alg/APG system solution and the APG system solution,and the deposition of bifenthrin of the H-Ugi-Alg/APG system solution on the banana leaves is also greater than that of the other two systems,which is mainly due to the hydrophobic interaction between Ugi-Alg and APG.Since H-Ugi-Alg is more easily adsorbed on the surfaces of banana leaf,the bifenthrin in the H-Ugi-Alg/APG system solution deposited on banana leaves is higher than that in the M-Ugi-Alg/APG system.Finally,in order to compare the adhesion,wettability and evaporation performance of different system solutions on the target surface.We first synthesized dopamine-modified sodium alginate?H-Alg-DA?by the amide reaction method,and proved that H-Alg-DA was successfully synthesized by ¹H nuclear magnetic resonance spectroscopy,UV-Vis,fourier transform infrared spectroscopy and gel chromatography.Then adhesion of H-Alg-DA/APG system solution droplets and H-Ugi-Alg/APG system solution droplets on the surface of modified Si O₂ and banana leaves was measured by high-speed camera,upright electric microscope and high performance liquid chromatograph,the results show that the adhesion of the H-Alg-DA/APG system solution droplets is better than that of the H-Ugi-Alg/APG system,and the adsorption of acetamiprid in the of H-Alg-DA/APG system solution on banana leaves is also higher than that of H-Ugi-Alg/APG system.Afterwards,the evaporation and wetting properties of H-Alg-DA/APG system solution droplets and H-Ugi-Alg/APG system solution droplets on the surface of banana leaves were studied by optical contact angle/surface tension measuring instrument,the results show that the wettability of the H-Alg-DA/APG system solution droplets is better than that of the H-Alg-DA/APG system solution,and the evaporation patterns of the solution droplets of the two systems on the surface of the banana leaf are both wetting mode.