Research On New Multifunctional Fluorescent Sensors Based On A Potassium Ion Probe

Potassium ion?K⁺?is a kind of important metal ions in human body.K⁺ plays a vital role in some biological processes and functions,such as maintaining the normal function of the kidney,regulating heartbeat and gene expression.The Abnormal K⁺ level is related to many diseases,including kidney dysfunction,heart disease,stroke,epilepsy and so on.Oxygen is an essential substance for the survival and growth of biologies including animals,plants and some microorganisms.Humans might only survive for a few minutes without oxygen.The regulation of K⁺ on various life activities is closely related to the dissolved oxygen?DO?.Therefore,it is very important to detect K⁺ concentration and DO concentration simultaneously.Herein,we reported the preparation of K⁺-O₂ dual sensing film.K⁺-O₂ dual sensing film contains three probes which are K⁺ probe?KS?,O₂ probe?OS?,and reference probe?RP?.The emission peaks of three probes do not interfere with each other,which enable the sensing film to be used for ratiometrically and quantitatively detecting the concentrations of K⁺ and DO.The sensing films showed good selectivity to K⁺ over other metal ions.The sensing films can respond well to broad K⁺ concentrations from 1 m M to 300 m M,and DO concentrations from 1 mg/L to 40.87 mg/L.The sensing films showed good sensitivity and high measurement accuracy to K⁺ and DO.The sensing film was demonstrated to be capable of analyzing K⁺ and DO concentrations with experimental errors smaller than ±8.5% in aqueous solutions.The dual sensing film has potential applications for the diagnosis of diseases and the study of pathology.