Cobalt-doped ZnO Nanoparticles Driven From Metal Organic Frameworks And Its Sensing Properties For Exhaled Diseases Biomarker

As a new type of functional nanomaterial,metal-organic frameworks(MOFs)are promising for building gas sensors.In recent years,the porous materials obtained from metal organic framework(MOFs)have a broad application prospect in catalysis,separation and sensing technology,and are favored by researchers.Metal-organic frameworks(MOFs)with porous structures,high surface areas,diverse compositions,and functional linkers are promising materials and good carriers for building high-performance devices.In this paper,the porous structure and diverse compositions nanomaterials were obtained by organic framework.Firstly,different metal organic frames were obtained by mixing in different proportions.After high temperature annealing treatment,the structure,surface state,dispensability,ferromagnetism and even the composite of the final oxide NPs could be adjusted.It was used to further improve the performance of sensing properties,then the acetone was detected as for a biomarker of diabetes.The main results are as follows:(1)It is an important method to design and prepare accurately doped semiconductor metal oxide nanoparticles.In order to achieve more active sites in nanomaterials,we prepared four kinds of metal organic framework(MOFs),when the molar ratio of Co/Zn(y/x)increased,the color of the obtained bimetallic ZIF NPs gradually changed from indigo to dark blue.The color of the obtained ZnxCoy oxide NPs changed to green,and the corresponding color gradually deepened from light green to brown–green with increasing amounts of Co.The regular and homogeneous arrangement of cobalt and zinc ions in the bimetallic ZIF NPs enabled a more controllable synthesis of the cobalt-doped(Co-doped)ZnO NPs.(2)A gas sensor modified by the low-cost,high stability and noninvasive diagnosis of diabetes.The Co-doped ZnO NPs were evaluated as a sensing material for diabetes biomarker detection;the obtained sensors showed a high response to trace acetone(18.2 at 5 ppm),fast response/recovery times,a low detection limit(170 ppb),and long-term stability for 4 months.The enhanced sensing performance can be attributed to the increased number of active sites,additional impurity energy levels,and the catalytic ability of elemental Co.Moreover,the optimized sensor could distinguish between simulated diabetic breath and healthy human breath samples.The MOF-derived Co-doped ZnO NPs are a good candidate for the low-cost and noninvasive diagnosis of diabetes,and the proposed synthesis strategy can be extended to other types of extrinsically doped oxide materials.In summary,based on the semiconductor nanomaterials with different doping ratios,we improved the sensitivity in different ways,and noninvasive diagnosis of diabetes,which has certain reference significance for one-step of co-doping.