Mesoscopic Phase Separation Behavior And Kinetics Of Cyclodextrin Complex/agarose Multi-component Gel System

Mesoscopic phase separation has the characteristics of high dimension,multi-level and multi-time dimensions.the structure and function of the ordered aggregates are diverse,so it has received extensive attention.However,there are still many issues that need to be discussed,such as the mesoscopic phase separation mechanism,precise adjustment,and expanding applications.This paper mainly focuses on the mesoscopic layered-fiber phase separation behavior of the cyclodextrin complex/agarose multi-component gel system to explore its mechanism and kinetics.At the same time,it combines thermodynamic models and experiments to explore the law of mesoscopic layered-fiber phase separation.This study improves the basic theory of mesoscopic phase separation and expands its scope of application.The research content of this thesis is mainly divided into the following three parts:(1)The research discussed the structure and characteristics of ordered aggregates formed by mesoscopic phase separation,and studied the assembly mechanism of layered aggregates.This paper constructed the phase diagram of the system and discovered the "memory effect" characteristics and dynamic assembly characteristics of layered aggregates through temperature-controlled microscopy.This work not only found this novel mesoscopic layered-fiber phase separation behavior,but also clearly understood the self-assembly characteristics of layered aggregates.(2)This paper studied the influence of the gel elastic modulus of the system on aggregates,and explored the morphology and distribution of aggregates in the cyclodextrin complex/concentration gradient DN double-network gel.At the same time this work pre-punched the array in the gel to achieve precise spatial control of the lamellar phase.This part of the work not only explores the influencing factors of mesoscopic laminar-fiber phase separation,but also opens up a new way for precise control of mesoscopic phase separation.(3)The research observed the evolution of mesoscopic laminar-fiber phase separation dynamic morphology through temperature-controlled microscopy,and explored the dynamics of lamellar dispersed phase and continuous fiber phase.This paper found that there are three dynamic stages of mesoscopic laminar-fiber phase separation: fiber network formation;tubularnucleus formation in fiber pores;and tubular nucleus expansion and growth outside the pores.The research studied the growth dynamics of the layered area and the stress field of the surrounding fibers.This paper also established a thermodynamic model to explore the mesoscopic layer-fiber phase separation law,and combined with experiments to verify its accuracy.This work not only enriches the mesoscopic phase separation system,but also provides an in-depth understanding of the normal regulation of organisms and the mechanism of disease.In summary,our research results not only enrich the mesoscopic phase separation system,but also have important significance for the study of mesoscopic phase separation mechanism.In terms of practical application,the research has certain reference value for the design and function regulation of new materials,as well as the understanding and disclosure of the regulation laws in living organisms.