| CO2 partial pressure monitoring is considered to be the sixth basic vital sign other than body temperature,respiration,pulse,blood pressure and arterial oxygen saturation.It has important clinical significance for judging lung ventilation,respiratory status and blood flow changes.Clinically,in the use of traditional non-invasive ventilator assisted ventilation,the monitoring of CO2 is generally performed by arterial blood gas analysis,which is invasive and cannot be continuously monitored.At present,dynamic continuous monitoring of CO2 during non-invasive ventilation is not possible.At present,the non-invasive ventilator has a single human-computer interaction mode and lacks the remote monitoring function of the ventilator.Therefore,this thesis designed a remote management non-invasive ventilator with CO2 monitoring function.We connected the end-tidal CO2 sensor module in the non-invasive ventilator pipeline and realized the end-tidal CO2 data transmission through Bluetooth.The same terminal displayed and achieved dynamic continuous monitoring of the end-tidal CO2 data and the routine parameter data of the ventilator.We solved the problem that it is difficult to cooperate with the end-tidal CO2 monitor when non-invasive ventilation,and it can make up for the failure to continuously monitor CO2 at the same time in the clinical use of non-invasive ventilator.The main contents of this paper are as follows:(1)The design of the connection scheme between the non-invasive ventilator and the end-tidal CO2 sensor module.This section details how to connect the end-tidal CO2 sensor module to the non-invasive ventilator line.The continuous dynamic monitoring of the end-tidal CO2 data is achieved by the Bluetooth transmission function.The schematic diagram of the connection scheme and the physical connection diagram are designed.Through this connection method,the continuous dynamic monitoring of the end-tidal CO2 and the real-time display of the human-computer interaction interface are successfully realized.In order to ensure accurate monitoring of end-tidal CO2 data during non-invasive ventilation,non-invasive ventilator and end-tidal CO2 monitor are required to cooperate with each other.This part is designed with specific coordination process flow and setting adjustment of non-invasive ventilator.The purpose is to make the end-tidal CO2 data monitoring accurate.Design of cloud platform for non-invasive ventilator remote management system with CO2 monitoring function.This part includes data transmission connection design,cloud platform system design and data management interface design.Through remote management of cloud platform design,the upload and save of end-tidal CO2 data is realized.(2)Accuracy evaluation study of end-tidal CO2 sensor module with non-invasive ventilator Bluetooth connection under different breathing conditions.The end-tidal CO2 and respiratory rate data under calm and deep breathing were monitored by comparison with mature end-tidal CO2 devices,Correlation and consistency analysis showed high correlation(>90%).With consistency,the results were statistically significant(p<0.05),indicating that the CO2 data monitored by this end-tidal CO2 sensor module was accurate.Evaluation of CO2 monitoring accuracy under different ventilation pressures of remote management non-invasive ventilators with CO2 monitoring function.The accuracy of the end-tidal CO2 monitoring data under different pressures was verified by comparison with the bypass end-tidal CO2 monitoring equipment.The correlation analysis showed that the non-invasive ventilator and the bypass end-tidal CO2 monitor with CO2 monitoring function were positively correlated.The consistency analysis showed that the average difference obtained was between(-0.67±0.55)mmHg and(-0.17±0.56)mmHg due to the different ventilation pressures.This fully demonstrates the accuracy of the end-tidal CO2 data monitored by this non-invasive ventilator.(3)Analysis of changes in the regulation of self-regulation of breathing under non-invasive ventilation.We used this non-invasive ventilator with CO2 monitoring function and monitored the tidal volume,respiratory rate and end-tidal CO2 at the same time.We studied the effect of tidal volume and respiratory rate on end-tidal CO2 during non-invasive ventilation using multiple linear regression.The regression model was established.The results showed that there was a self-regulation mechanism between tidal volume and respiratory rate during non-invasive ventilation to maintain a relatively stable respiratory state. |
