Research On The Key Technology Of Dual-wavelength Interventional Hemoglobin Concentration Monitoring

Hemoglobin is an indispensable protein of the human body,and its content is an important physiological index reflecting the health status of the human blood.It is an important parameter to judge whether the human body is deficient in oxygen and to measure the ability of the human blood to carry oxygen.At present,invasive detection of human hemoglobin concentration is mainly used in clinical practice.This method cannot achieve continuous and real-time monitoring of the patient's hemoglobin concentration,and it will increase patient suffering.The existing non-invasive detection methods have problems such as inconsistent standards,and low precision and accuracy of measurement results.In order to achieve accurate,continuous,and real-time monitoring of changes in human hemoglobin concentration,especially to provide doctors with real-time and accurate blood oxygen parameters during surgery,this paper deeply researches Lambert-Beer Law and Infrared spectrum detection technology.Based on the study of these two theories,we analyze and discuss the relationship between human blood oxygen parameters and optical parameters.And we propose and build a dual-wa-velength interventional hemoglobin concentration monitoring system.The monitoring system has strong applicability,simple measurement process,and avoids the influence of different individuals,different thicknesses,and different locations on the hemoglobin concentration detection results.The minimally invasive method enables accurate monitoring of hemoglobin content in various parts of the human body.The minimally invasive interventional hemoglobin concentration monitoring system designed in this paper is composed of the lower computer hardware circuit and the upper computer software.The hardware part of the lower computer mainly includes STM32-based control system,dual-wavelength front-end detection probe,I-V conversion module,operational amplifier module,power supply voltage conversion module,and USB serial communication module.This paper designs human-computer interaction interface through LABVIEW software development environment to realize the functions of related modules,and mainly performs arithmetic processing on the collected data,and displays and saves it.The system collects the light intensity signal of the detection light and combines the interventional hemoglobin concentration detection algorithm for human hemoglobin content.The system was used to test the red ink solution and blood samples in order to explore the relationship between the concentration of the liquid to be tested,the thickness of the liquid layer and the emitted light intensity,then the paper conducts a qualitative analysis of the experimental results.The test results satisfactorily met Lambert-Beer Law to provide a basis for the next quantitative analysis.A total of 60 heterosexual subjects(equal numbers of men and women)were collected for testing in the experiment.The first set of experimental samples were blood samples from 10 subjects(equal numbers of men and women)randomly selected from 60.It performed 10 consecutive repeated measurements with the largest mean square error ?=0.8390 of the test results,indicating that the hemoglobin concentration monitoring system has good stability;the blood samples of the remaining 50 heterosexual subjects were used as the second set of experimental samples,and take a single measurement of them,comparing the measured value with the real value measured by the hospital,the maximum error of the experimental result is 4.96%,and the correlation coefficient is not less than 0.8806,and the experimental results are all within the 95%consistency limit of the Bland-Altman diagram,proving that the system has high accuracy and reliability,and it can measure human hemoglobin content more accurately and reflect the trend of blood oxygen change,and provide an important reference for clinical detection of blood transport.This paper combines optical fiber sensing technology with clinical medicine,and in-depth studies on dual-wavelength minimally invasive interventional hemoglobin concentration monitoring methods.The research results will play an important guiding role in clinical medicine,especially surgery.